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Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or...

8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters: an acylcholine + H2O = choline + a...

acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of...

cord via reticulospinal tract.[citation needed] Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine and causes a rise...

breakdown of acetylcholine and some other choline esters that function as neurotransmitters: acetylcholine + H2O = choline + acetate It is found at mainly neuromuscular...

inhibition the substrate and inhibitor cannot bind to the enzyme at the same time.: 134  This usually results from the inhibitor having an affinity for the...

pseudocholinesterase, or plasma (cholin)esterase, is a nonspecific cholinesterase enzyme that hydrolyses many different choline-based esters. In humans, it is...

The knowledge of the effects of low doses of soman and other choline esterase inhibitors on rats could possibly be used to explain the relatively high...

Ganaton) is a prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. Itopride is indicated...

but its metabolism starts in the intestines where it is metabolized by esterase into a thiolactone, this inactive intermediate then undergoes CYP-mediated...

Alzheimer's dementia) are modest, and it is still unclear which AChE (BChE) esterase inhibitor is better in Parkinson's dementia, though rivastigmine is well-studied...

acetylcholine in the neuromuscular junction into acetate and choline. Neostigmine is an inhibitor of acetylcholinesterase. Neostigmine binds to the anionic...

name Provocholine), also known as acetyl-β-methylcholine, is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic...

containing serine at the active site, e g. Serine proteases, acetylcholine esterase. Isoflurophate, the diisopropyl ester of fluorophosphoric acid, is made...

Quastel, J. H.; Tennenbaum, M.; Wheatley, A. H. (1936). "Choline ester formation in, and choline esterase activities of, tissues in vitro". The Biochemical Journal...

Acetylcholine is synthesized in the cytoplasm of the neuron from choline and acetyl-CoA. Choline acetyltransferase is the enzyme that synthesizes acetylcholine...

bacterial autolysins. A Nocardia aerocolonigenes putative esterase. Streptococcus pneumoniae choline-binding protein D. Methanosarcina mazei protein MM2478...

dietary supplement. Acetylcarnitine is broken down in the blood by plasma esterases to carnitine which is used by the body to transport fatty acids into the...

μ-opioid receptor, and tramadol is a serotonin norepinephrine reuptake inhibitor (SNRI) with weak μ-opioid receptor agonist properties. Tramadol is structurally...

metabolism. Organophosphorus pesticides like Disulfoton inhibit esterase enzyme activity like choline esterase. These types of pesticides can also directly interact...