Necrotizing pneumonia: Difference between revisions
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Revision as of 19:36, 19 February 2021
| Necrotizing pneumonia | |
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| File:Necrotic pneumonia with empyema and lung necrosis.jpg | |
| Moderate sized left effusion with underlying consolidation. Notice the contralateral mediastinal shift suggesting that there is not a significant amount of collapse. | |
| Specialty | Infectious disease, respirology |
Necrotizing pneumonia (NP), also known as cavitary pneumonia or cavitatory necrosis, is a rare but severe complication of lung parenchymal infection.[1][2][3] In necrotizing pneumonia, there is a substantial liquefaction following death of the lung tissue, which may lead to gangrene foramtion in the lung.[4][5] In most cases patients with NP have fever, cough and bad breath, and those with more indolent infections have weight loss.[6] Often patients clinically present with acute respiratory failure.[6] The most common pathogens responsible for NP are Streptococcus pneumonia, Staphylococcus aureus (mostly MRSA), Klebsiella pneumoniae, Streptococcus pyogenes.[7] Diagnosis is usually done by chest imaging, e.g. chest X-ray, CT scan. Among these CT scan is the most sensitive test which shows loss of lung architecture and multiple small thin walled cavities.[3] Often cultures from bronchoalveolar lavage and blood may be done for identification of the causative organism(s).[8] It is primarily managed by supportive care along with appropriate antibiotics.[8] However, if patient develops severe complications like sepsis or fails to medical therapy, surgical resection is a reasonable option for saving life.[8][6]
Reference
- ^ Sawicki, G. S.; Lu, F. L.; Valim, C.; Cleveland, R. H.; Colin, A. A. (2008-03-05). "Necrotising pneumonia is an increasingly detected complication of pneumonia in children". European Respiratory Journal. 31 (6). European Respiratory Society (ERS): 1285–1291. doi:10.1183/09031936.00099807. ISSN 0903-1936.
- ^ Tsai, Yueh-Feng; Ku, Yee-Huang (2012). "Necrotizing pneumonia". Current Opinion in Pulmonary Medicine. 18 (3): 246–252. doi:10.1097/MCP.0b013e3283521022. ISSN 1070-5287.
- ^ a b Masters, I. Brent; Isles, Alan F.; Grimwood, Keith (July 25, 2017). "Necrotizing pneumonia: an emerging problem in children?". Pneumonia. 9 (1). Springer Science and Business Media LLC. doi:10.1186/s41479-017-0035-0. ISSN 2200-6133.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Scotta, Marcelo C.; Marostica, Paulo J.C.; Stein, Renato T. (2019). "Pneumonia in Children". Kendig's Disorders of the Respiratory Tract in Children. Elsevier. p. 435.e4. doi:10.1016/b978-0-323-44887-1.00025-0. ISBN 978-0-323-44887-1.
- ^ Widysanto, Allen; Liem, Maranatha; Puspita, Karina Dian; Pradhana, Cindy Meidy Leony. "Management of necrotizing pneumonia with bronchopleural fistula caused by multidrug‐resistant Acinetobacter baumannii". Respirology Case Reports. 8 (8). doi:10.1002/rcr2.662. PMID 32999723. Retrieved February 19, 2021.
- ^ a b c Reimel, Beth Ann; Krishnadasen, Baiya; Cuschieri, Joseph; Klein, Matthew B; Gross, Joel; Karmy-Jones, Riyad (January 1, 2000). "Surgical management of acute necrotizing lung infections". Canadian Respiratory Journal : Journal of the Canadian Thoracic Society. 13 (7). doi:10.1155/2006/760390. PMID 17036090. Retrieved February 19, 2021.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Norte A, Santos C, Gamboa F, Gamboa F, Ferreira AJ, Marques A, Leite C,Robalo Cordeiro C (January 2012). "[Necrotizing pneumonia - a rare complication]". Acta medica portuguesa. 25 (1). ISSN 1646-0758. PMID 22883249.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ a b c Chatha, Neela; Fortin, Dalilah; Bosma, Karen J (February 19, 2021). "Management of necrotizing pneumonia and pulmonary gangrene: A case series and review of the literature". Canadian Respiratory Journal : Journal of the Canadian Thoracic Society. 21 (4). doi:10.1155/2014/864159. PMID 24791253. Retrieved February 19, 2021.
{{cite journal}}: CS1 maint: unflagged free DOI (link)