SEMA5A: Difference between revisions
Content deleted Content added
Shwang0906 (talk | contribs) m Added reference |
replace primary with secondary source; consistent citation formatting; removed further reading citations not specific to this gene |
||
| Line 1: | Line 1: | ||
{{Infobox_gene}} |
{{Infobox_gene}} |
||
'''Semaphorin-5A''' is a [[protein]] that in humans is encoded by the ''SEMA5A'' [[gene]].<ref name=" |
'''Semaphorin-5A''' is a [[protein]] that in humans is encoded by the ''SEMA5A'' [[gene]].<ref name="Adams_1997">{{cite journal | vauthors = Adams RH, Betz H, Püschel AW | title = A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis | journal = Mechanisms of Development | volume = 57 | issue = 1 | pages = 33–45 | date = June 1996 | pmid = 8817451 | doi = 10.1016/0925-4773(96)00525-4 | s2cid = 17827262 | doi-access = free }}</ref><ref name="pmid9464278">{{cite journal | vauthors = Simmons AD, Püschel AW, McPherson JD, Overhauser J, Lovett M | title = Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval | journal = Biochemical and Biophysical Research Communications | volume = 242 | issue = 3 | pages = 685–691 | date = January 1998 | pmid = 9464278 | doi = 10.1006/bbrc.1997.8027 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9037}}</ref> |
||
Members of the semaphorin protein family, such as SEMA5A, are involved in [[axonal guidance]] during [[neural development]] |
Members of the semaphorin protein family, such as SEMA5A, are involved in [[axonal guidance]] during [[neural development]].<ref name="entrez">{{cite web | title = Entrez Gene: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9037}}</ref><ref name="Adams_1997" /> |
||
Semaphorin 5A also plays a role in [[autism]], reducing the ability of [[neurons]] to form connections with other neurons in certain brain regions.<ref name="pmid26395558">{{cite journal | vauthors = Mosca-Boidron AL, Gueneau L, Huguet G, Goldenberg A, Henry C, Gigot N, Pallesi-Pocachard E, Falace A, Duplomb L, Thevenon J, Duffourd Y, St-Onge J, Chambon P, Rivière JB, Thauvin-Robinet C, Callier P, Marle N, Payet M, Ragon C, Goubran Botros H, Buratti J, Calderari S, Dumas G, Delorme R, Lagarde N, Pinoit JM, Rosier A, Masurel-Paulet A, Cardoso C, Mugneret F, Saugier-Veber P, Campion D, Faivre L, Bourgeron T | display-authors = 6 | title = A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability | journal = European Journal of Human Genetics | volume = 24 | issue = 6 | pages = 838–843 | date = June 2016 | pmid = 26395558 | pmc = 4867450 | doi = 10.1038/ejhg.2015.211 }}</ref><ref name="pmid34045951">{{cite journal | vauthors = Carulli D, de Winter F, Verhaagen J | title = Semaphorins in Adult Nervous System Plasticity and Disease | journal = Frontiers in Synaptic Neuroscience | volume = 13 | issue = | pages = 672891 | date = 2021 | pmid = 34045951 | pmc = 8148045 | doi = 10.3389/fnsyn.2021.672891 }}</ref> |
|||
Semaphorine 5A also plays a role in [[autism]], reducing the ability of [[neurons]] to form connections with other neurons in certain brain regions (Mosca-Boidron et al 2016)<ref>{{Cite journal |last=Duan |first=Yuntao |last2=Wang |first2=Shih-Hsiu |last3=Song |first3=Juan |last4=Mironova |first4=Yevgeniya |last5=Ming |first5=Guo-li |last6=Kolodkin |first6=Alex L. |last7=Giger |first7=Roman J. |date=2014-10-14 |title=Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells |url=https://pubmed.ncbi.nlm.nih.gov/25313870 |journal=eLife |volume=3 |doi=10.7554/eLife.04390 |issn=2050-084X |pmc=4236683 |pmid=25313870}}</ref>. |
|||
==References== |
== References == |
||
{{reflist}} |
{{reflist}} |
||
==Further reading== |
== Further reading == |
||
{{refbegin | 2}} |
{{refbegin | 2}} |
||
*{{cite journal |
* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }} |
||
*{{cite journal |
* {{cite journal | vauthors = Simmons AD, Overhauser J, Lovett M | title = Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library | journal = Genome Research | volume = 7 | issue = 2 | pages = 118–127 | date = February 1997 | pmid = 9049630 | doi = 10.1101/gr.7.2.118 | doi-access = free }} |
||
*{{cite journal |
* {{cite journal | vauthors = Artigiani S, Conrotto P, Fazzari P, Gilestro GF, Barberis D, Giordano S, Comoglio PM, Tamagnone L | display-authors = 6 | title = Plexin-B3 is a functional receptor for semaphorin 5A | journal = EMBO Reports | volume = 5 | issue = 7 | pages = 710–714 | date = July 2004 | pmid = 15218527 | pmc = 1299100 | doi = 10.1038/sj.embor.7400189 }} |
||
*{{cite journal |
* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | display-authors = 6 | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–12135 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | doi-access = free | bibcode = 2004PNAS..10112130B }} |
||
* {{cite journal | vauthors = Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM | display-authors = 6 | title = The DNA sequence and comparative analysis of human chromosome 5 | journal = Nature | volume = 431 | issue = 7006 | pages = 268–274 | date = September 2004 | pmid = 15372022 | doi = 10.1038/nature02919 | doi-access = free | bibcode = 2004Natur.431..268S }} |
|||
*{{cite journal |vauthors=Artigiani S, Conrotto P, Fazzari P, etal |title=Plexin-B3 is a functional receptor for semaphorin 5A. |journal=EMBO Rep. |volume=5 |issue= 7 |pages= 710–4 |year= 2005 |pmid= 15218527 |doi= 10.1038/sj.embor.7400189 | pmc=1299100 }} |
|||
| ⚫ | * {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | display-authors = 6 | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = January 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }} |
||
*{{cite journal |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |doi-access=free }} |
|||
*{{cite journal |
* {{cite journal | vauthors = Melin M, Carlsson B, Anckarsater H, Rastam M, Betancur C, Isaksson A, Gillberg C, Dahl N | display-authors = 6 | title = Constitutional downregulation of SEMA5A expression in autism | journal = Neuropsychobiology | volume = 54 | issue = 1 | pages = 64–69 | year = 2007 | pmid = 17028446 | pmc = 2553518 | doi = 10.1159/000096040 }} |
||
*{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} |
|||
| ⚫ | *{{cite journal |
||
*{{cite journal |vauthors=Melin M, Carlsson B, Anckarsater H, etal |title=Constitutional downregulation of SEMA5A expression in autism. |journal=Neuropsychobiology |volume=54 |issue= 1 |pages= 64–9 |year= 2007 |pmid= 17028446 |doi= 10.1159/000096040 | pmc=2553518 |url=http://www.hal.inserm.fr/inserm-00124743/document }} |
|||
{{refend}} |
{{refend}} |
||
Revision as of 02:56, 24 May 2022
Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene.[5][6][7]
Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development.[7][5]
Semaphorin 5A also plays a role in autism, reducing the ability of neurons to form connections with other neurons in certain brain regions.[8][9]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000112902 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022231 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Adams RH, Betz H, Püschel AW (June 1996). "A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis". Mechanisms of Development. 57 (1): 33–45. doi:10.1016/0925-4773(96)00525-4. PMID 8817451. S2CID 17827262.
- ^ Simmons AD, Püschel AW, McPherson JD, Overhauser J, Lovett M (January 1998). "Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval". Biochemical and Biophysical Research Communications. 242 (3): 685–691. doi:10.1006/bbrc.1997.8027. PMID 9464278.
- ^ a b "Entrez Gene: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A".
- ^ Mosca-Boidron AL, Gueneau L, Huguet G, Goldenberg A, Henry C, Gigot N, et al. (June 2016). "A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability". European Journal of Human Genetics. 24 (6): 838–843. doi:10.1038/ejhg.2015.211. PMC 4867450. PMID 26395558.
- ^ Carulli D, de Winter F, Verhaagen J (2021). "Semaphorins in Adult Nervous System Plasticity and Disease". Frontiers in Synaptic Neuroscience. 13: 672891. doi:10.3389/fnsyn.2021.672891. PMC 8148045. PMID 34045951.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
Further reading
- Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Simmons AD, Overhauser J, Lovett M (February 1997). "Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library". Genome Research. 7 (2): 118–127. doi:10.1101/gr.7.2.118. PMID 9049630.
- Artigiani S, Conrotto P, Fazzari P, Gilestro GF, Barberis D, Giordano S, et al. (July 2004). "Plexin-B3 is a functional receptor for semaphorin 5A". EMBO Reports. 5 (7): 710–714. doi:10.1038/sj.embor.7400189. PMC 1299100. PMID 15218527.
- Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, et al. (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–12135. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, et al. (September 2004). "The DNA sequence and comparative analysis of human chromosome 5". Nature. 431 (7006): 268–274. Bibcode:2004Natur.431..268S. doi:10.1038/nature02919. PMID 15372022.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, et al. (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Melin M, Carlsson B, Anckarsater H, Rastam M, Betancur C, Isaksson A, et al. (2007). "Constitutional downregulation of SEMA5A expression in autism". Neuropsychobiology. 54 (1): 64–69. doi:10.1159/000096040. PMC 2553518. PMID 17028446.
 | This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it. |