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'''Ultra-processed foods''' (UPFs) are industrially formulated edible substances derived from [[natural food]] or synthesized from other organic sources.<ref>{{Cite journal |last=Monteiro |first=Carlos |date=2010 |title=The big issue is ultra-processing |url=https://wphna.org/worldnutritionjournal/index.php/wn/article/view/535 |journal=World Nutrition |language=en |volume=1 |issue=6 |pages=237–269 |issn=2041-9775}}</ref><ref>{{Cite journal |last=Monteiro |first=Carlos |date=2011 |title=The big issue is ultra-processing. Why bread, hot dogs – and margarine – are ultra-processed |url=https://wphna.org/worldnutritionjournal/index.php/wn/article/view/452 |journal=World Nutrition |language=en |volume=2 |issue=10 |pages=534–549 |issn=2041-9775}}</ref> These products often contain [[Food additive|additives]] such as [[Food coloring|colourings]], [[Flavoring|flavourings]], and [[Preservative|preservatives]], and are designed to be [[Convenience food|convenient]], hyper-palatable, and have a long [[shelf life]].<ref name="Monteiro2019">{{Cite journal |last1=Monteiro |first1=Carlos A. |last2=Cannon |first2=Geoffrey |last3=Levy |first3=Renata B |last4=Moubarac |first4=Jean-Claude |last5=Louzada |first5=Maria L. C. |last6=Rauber |first6=Fernanda |last7=Khandpur |first7=Neha |last8=Cediel |first8=Gustavo |last9=Neri |first9=Daniela |last10=Martinez-Steele |first10=Euridice |last11=Baraldi |first11=Larissa G. |last12=Jaime |first12=Patricia C. |date=2019 |title=Ultra-processed foods: what they are and how to identify them |journal=Public Health Nutrition |language=en |volume=22 |issue=5 |pages=936–941 |doi=10.1017/S1368980018003762 |issn=1368-9800 |pmc=10260459 |pmid=30744710 |doi-access=free}}</ref>
'''Ultra-processed foods''' (UPFs) are industrially formulated edible substances derived from [[natural food]] or synthesized from other organic sources.<ref>{{Cite journal |last=Monteiro |first=Carlos |date=2010 |title=The big issue is ultra-processing |url=https://wphna.org/worldnutritionjournal/index.php/wn/article/view/535 |journal=World Nutrition |language=en |volume=1 |issue=6 |pages=237–269 |issn=2041-9775}}</ref><ref>{{Cite journal |last=Monteiro |first=Carlos |date=2011 |title=The big issue is ultra-processing. Why bread, hot dogs – and margarine – are ultra-processed |url=https://wphna.org/worldnutritionjournal/index.php/wn/article/view/452 |journal=World Nutrition |language=en |volume=2 |issue=10 |pages=534–549 |issn=2041-9775}}</ref> These products often contain [[Food additive|additives]] such as [[Food coloring|colourings]], [[Flavoring|flavourings]], and [[Preservative|preservatives]], and are designed to be [[Convenience food|convenient]], hyper-palatable, and have a long [[shelf life]].<ref name="Monteiro2019">{{Cite journal |last1=Monteiro |first1=Carlos A. |last2=Cannon |first2=Geoffrey |last3=Levy |first3=Renata B |last4=Moubarac |first4=Jean-Claude |last5=Louzada |first5=Maria L. C. |last6=Rauber |first6=Fernanda |last7=Khandpur |first7=Neha |last8=Cediel |first8=Gustavo |last9=Neri |first9=Daniela |last10=Martinez-Steele |first10=Euridice |last11=Baraldi |first11=Larissa G. |last12=Jaime |first12=Patricia C. |date=2019 |title=Ultra-processed foods: what they are and how to identify them |journal=Public Health Nutrition |language=en |volume=22 |issue=5 |pages=936–941 |doi=10.1017/S1368980018003762 |issn=1368-9800 |pmc=10260459 |pmid=30744710 |doi-access=free}}</ref>


The state of research into ultra-processed foods and their effects is evolving rapidly as of 2023.<ref name="Touvier2023">{{Cite journal |last=Touvier |first=Mathilde |last2=Louzada |first2=Maria Laura da Costa |last3=Mozaffarian |first3=Dariush |last4=Baker |first4=Phillip |last5=Juul |first5=Filippa |last6=Srour |first6=Bernard |date=2023-10-09 |title=Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait |journal=BMJ |language=en |volume=383 |pages=e075294 |doi=10.1136/bmj-2023-075294 |issn=1756-1833 |pmc=10561017 |pmid=37813465 |doi-access=free}}</ref> The most common definition of ultra-processed food is from the [[Nova classification]], but there are also other proposals.<ref>{{Cite journal |last1=Fardet |first1=Anthony |last2=Rock |first2=Edmond |date=2019-11-01 |title=Ultra-processed foods: A new holistic paradigm? |journal=Trends in Food Science & Technology |volume=93 |pages=174–184 |doi=10.1016/j.tifs.2019.09.016 |s2cid=203896042 |issn=0924-2244}}</ref> [[Nutritional epidemiology|Epidemiological data]] suggest that consumption of ultra-processed foods is associated with higher risks of certain diseases, including [[obesity]], [[type 2 diabetes]], [[Cardiovascular disease|cardiovascular diseases]], and certain types of [[cancer]].<ref name="Pagliai2021">{{Cite journal |last1=Pagliai |first1=G. |last2=Dinu |first2=M. |last3=Madarena |first3=M. P. |last4=Bonaccio |first4=M. |last5=Iacoviello |first5=L. |last6=Sofi |first6=F. |date=2021-02-14 |title=Consumption of ultra-processed foods and health status: a systematic review and meta-analysis |journal=British Journal of Nutrition |language=en |volume=125 |issue=3 |pages=308–318 |doi=10.1017/S0007114520002688 |issn=0007-1145 |pmc=7844609 |pmid=32792031}}</ref> Researchers also present ultra-processing as a facet of [[environmental degradation]] caused by the [[food industry]].<ref name="Leite2022">{{Cite journal |last1=Leite |first1=Fernanda Helena Marrocos |last2=Khandpur |first2=Neha |last3=Andrade |first3=Giovanna Calixto |last4=Anastasiou |first4=Kim |last5=Baker |first5=Phillip |last6=Lawrence |first6=Mark |last7=Monteiro |first7=Carlos Augusto |date=2022-03-01 |title=Ultra-processed foods should be central to global food systems dialogue and action on biodiversity |journal=BMJ Global Health |language=en |volume=7 |issue=3 |pages=e008269 |doi=10.1136/bmjgh-2021-008269 |issn=2059-7908 |pmc=8895941 |pmid=35346976}}</ref>
The state of research into ultra-processed foods and their effects is evolving rapidly as of 2023.<ref name="Touvier2023">{{Cite journal |last=Touvier |first=Mathilde |last2=Louzada |first2=Maria Laura da Costa |last3=Mozaffarian |first3=Dariush |last4=Baker |first4=Phillip |last5=Juul |first5=Filippa |last6=Srour |first6=Bernard |date=2023-10-09 |title=Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait |journal=BMJ |language=en |volume=383 |pages=e075294 |doi=10.1136/bmj-2023-075294 |issn=1756-1833 |pmc=10561017 |pmid=37813465 |doi-access=free}}</ref> The most common definition of ultra-processed food is from the [[Nova classification]], but there are also other proposals.<ref>{{Cite journal |last1=Fardet |first1=Anthony |last2=Rock |first2=Edmond |date=2019-11-01 |title=Ultra-processed foods: A new holistic paradigm? |journal=Trends in Food Science & Technology |volume=93 |pages=174–184 |doi=10.1016/j.tifs.2019.09.016 |s2cid=203896042 |issn=0924-2244}}</ref><ref>{{Cite journal |last=Moubarac |first=Jean-Claude |last2=Parra |first2=Diana C. |last3=Cannon |first3=Geoffrey |last4=Monteiro |first4=Carlos A. |date=2014-06-01 |title=Food Classification Systems Based on Food Processing: Significance and Implications for Policies and Actions: A Systematic Literature Review and Assessment |journal=Current Obesity Reports |language=en |volume=3 |issue=2 |pages=256–272 |doi=10.1007/s13679-014-0092-0 |issn=2162-4968}}</ref> [[Nutritional epidemiology|Epidemiological data]] suggest that consumption of ultra-processed foods is associated with higher risks of certain diseases, including [[obesity]], [[type 2 diabetes]], [[Cardiovascular disease|cardiovascular diseases]], and certain types of [[cancer]].<ref name="Pagliai2021">{{Cite journal |last1=Pagliai |first1=G. |last2=Dinu |first2=M. |last3=Madarena |first3=M. P. |last4=Bonaccio |first4=M. |last5=Iacoviello |first5=L. |last6=Sofi |first6=F. |date=2021-02-14 |title=Consumption of ultra-processed foods and health status: a systematic review and meta-analysis |journal=British Journal of Nutrition |language=en |volume=125 |issue=3 |pages=308–318 |doi=10.1017/S0007114520002688 |issn=0007-1145 |pmc=7844609 |pmid=32792031}}</ref> Researchers also present ultra-processing as a facet of [[environmental degradation]] caused by the [[food industry]].<ref name="Leite2022">{{Cite journal |last1=Leite |first1=Fernanda Helena Marrocos |last2=Khandpur |first2=Neha |last3=Andrade |first3=Giovanna Calixto |last4=Anastasiou |first4=Kim |last5=Baker |first5=Phillip |last6=Lawrence |first6=Mark |last7=Monteiro |first7=Carlos Augusto |date=2022-03-01 |title=Ultra-processed foods should be central to global food systems dialogue and action on biodiversity |journal=BMJ Global Health |language=en |volume=7 |issue=3 |pages=e008269 |doi=10.1136/bmjgh-2021-008269 |issn=2059-7908 |pmc=8895941 |pmid=35346976}}</ref>


== Definition ==
== Definition ==

Revision as of 19:50, 14 October 2023

Potato chips and other ultra-processed foods in an American supermarket

Ultra-processed foods (UPFs) are industrially formulated edible substances derived from natural food or synthesized from other organic sources.[1][2] These products often contain additives such as colourings, flavourings, and preservatives, and are designed to be convenient, hyper-palatable, and have a long shelf life.[3]

The state of research into ultra-processed foods and their effects is evolving rapidly as of 2023.[4] The most common definition of ultra-processed food is from the Nova classification, but there are also other proposals.[5][6] Epidemiological data suggest that consumption of ultra-processed foods is associated with higher risks of certain diseases, including obesity, type 2 diabetes, cardiovascular diseases, and certain types of cancer.[7] Researchers also present ultra-processing as a facet of environmental degradation caused by the food industry.[8]

Definition

Label for NOVA group 4, 'ultra-processed foods'

Carlos Augusto Monteiro, working with a team of researchers at the University of São Paulo, first published the concept of ultra-processed foods in a 2009 invited commentary for Public Health Nutrition:[9]

Ultra-processed foods are basically confections of group 2 ingredients [substances extracted from whole foods], typically combined with sophisticated use of additives, to make them edible, palatable, and habit-forming. They have no real resemblance to group 1 foods [minimally processed foods], although they may be shaped, labelled and marketed so as to seem wholesome and 'fresh'. Unlike the ingredients included in group 2, ultra-processed foods are typically not consumed with or as part of minimally processed foods, dishes and meals. On the contrary, they are designed to be ready-to-eat (sometimes with addition of liquid such as milk) or ready-to-heat, and are often consumed alone or in combination (such as savoury snacks with soft drinks, bread with burgers).[10]

This definition is as much social as one based on specific ingredients, which makes the understanding of ultra-processed foods highly intuitive, even among untrained consumers.[11][12] This has also led to disagreement from researchers in food science on whether the definition can form a valid basis for scientific control.[13] A letter in response to Monteiro summarizes most of the scientific criticisms that have since followed ultra-processed food, suggesting that the definition 'lacks precision'.[14]

The same researchers subsequently used ultra-processed foods as a group in the Nova food classification system.[15] The system focuses on food processing rather than foods types or nutrients. Nova categorizes foods into four groups:[3]

  1. Unprocessed or minimally processed foods
  2. Processed culinary ingredients
  3. Processed foods
  4. Ultra-processed foods

Nova is an open classification that refines its definitions gradually through new scientific publications rather than through a central advisory board.[9] The most recent overview of Nova published with Monteiro defines ultra-processed food as follows:

Industrially manufactured food products made up of several ingredients (formulations) including sugar, oils, fats and salt (generally in combination and in higher amounts than in processed foods) and food substances of no or rare culinary use (such as high-fructose corn syrup, hydrogenated oils, modified starches and protein isolates). Group 1 foods are absent or represent a small proportion of the ingredients in the formulation. Processes enabling the manufacture of ultra-processed foods include industrial techniques such as extrusion, moulding and pre-frying; application of additives including those whose function is to make the final product palatable or hyper-palatable such as flavours, colourants, non-sugar sweeteners and emulsifiers; and sophisticated packaging, usually with synthetic materials. Processes and ingredients here are designed to create highly profitable (low-cost ingredients, long shelf-life, emphatic branding), convenient (ready-to-(h)eat or to drink), tasteful alternatives to all other Nova food groups and to freshly prepared dishes and meals. Ultra-processed foods are operationally distinguishable from processed foods by the presence of food substances of no culinary use (varieties of sugars such as fructose, high-fructose corn syrup, ‘fruit juice concentrates’, invert sugar, maltodextrin, dextrose and lactose; modified starches; modified oils such as hydrogenated or interesterified oils; and protein sources such as hydrolysed proteins, soya protein isolate, gluten, casein, whey protein and ‘mechanically separated meat’) or of additives with cosmetic functions (flavours, flavour enhancers, colours, emulsifiers, emulsifying salts, sweeteners, thickeners and anti-foaming, bulking, carbonating, foaming, gelling and glazing agents) in their list of ingredients.[16]

The concept of ultra-processed foods is not universally accepted and is under discussion among nutrition and public health scientists. The category does not comment on the nutritional content of food, meaning that it cannot be used for nutrient profiling.[17]

Economics

Ultra-processed foods are an important part of the portfolio of the food industry because they rely on low cost ingredients and often enjoy higher profit margins.[18] They often have an extended shelf life, an important consideration for lower income consumers without reliable access to refrigeration. Among other reasons for the popularity of ultra-processed foods are the inexpensive cost of their main ingredients and aggressive marketing, especially toward youth consumers and particularly in middle income countries.[19][20]

Health effects

Numerous research studies have linked the consumption of ultra-processed foods to an array of health issues. The high levels of sugar, fat, and salt in these foods, coupled with their low fibre content, have been associated with an increased risk of non-communicable diseases. High consumption of ultra-processed foods has been linked with obesity, hypertension, high cholesterol, and type 2 diabetes.[7][21]

Moreover, studies have indicated a potential association between the consumption of ultra-processed foods and an increased risk of some cancers. The exact mechanisms underlying these associations are not fully understood, but potential factors could include the presence of contaminants, certain food additives, and the high heat treatment of these foods, which can lead to the formation of potentially harmful compounds.[22]

Environmental impact

Beyond health implications, the production of ultra-processed foods also has significant environmental impacts.[8] These foods require extensive processing and packaging, resulting in higher energy consumption and waste production compared to minimally processed foods. Moreover, the globalized supply chains for the ingredients of ultra-processed foods contribute to greenhouse gas emissions.[23]

Regulation and policy

Given the health and environmental impacts of ultra-processed foods, there have been calls for better regulation and policy surrounding these products. These measures face significant challenges, including industry opposition and the global nature of food supply chains. Future policy efforts may require a combination of regulation, education, and incentives to promote healthier, more sustainable food choices.

Four Latin American countries—Brazil,[24] Uruguay,[25] Peru,[26] and Ecuador[27]—have so far published national official dietary guidelines that recommend avoiding ultra-processed foods. Chile requires warning labels on some ultra-processed foods and taxes sugar-sweetened beverages.[28] A report on obesity published by the World Bank in 2020 mentions ultra-processed foods as a potential contributor.[29]

Following the publication of the Nova classification, some researchers questioned whether food processing should itself be considered a factor in nutrient intake, especially in a prominent 2017 criticism written by researchers funded by Nestlé and the Kerry Group.[30] A study in 2020 that set out to disprove the correlation between the eating of ultra-processed foods and obesity instead found a strong link.[31] Dozens of earlier studies also found that food processing was a key element of health outcomes as shown in a 2021 review article.[32]

In 2022, Carlos Monteiro and Arne Astrup argued for and against the Nova classification in a series of three articles written in the style of an Oxford debate. Montiero argued, for the 'yes' side:

The recommendation to prefer unprocessed/minimally processed foods and freshly made meals instead of ultra-processed foods (following the Nova food classification system) is being increasingly adopted in new official dietary guidelines issued by national governments and international health associations. This recommendation is supported by systematic reviews and meta-analyses of nationally representative dietary surveys and long-term cohort studies. These data show that increased intake of ultra-processed foods is associated with poor-quality diets and with increased morbidity and mortality from several chronic diseases. Various attributes of ultra-processed foods acting through known, plausible, or suggested physiologic and behavioral mechanisms relate them to ill health, and it is likely that different combinations of attributes and mechanisms affect different health outcomes. Although more research should be done to identify these mechanisms, existing evidence is sufficient to recommend the avoidance of ultra-processed foods to optimize health and policies to support and make feasible this recommendation.[33]

Astrup's 'no' argument centres on the Nova definition of ultra-processed foods as not yet sufficiently proven by scientific research for broad application in public health policy:

Clearly, many aspects of food processing can affect health outcomes, but conflating them into the notion of ultra-processing is unnecessary, because the main determinants of chronic disease risk are already captured by existing nutrient profiling systems. In conclusion, the Nova classification adds little to existing nutrient profiling systems; characterizes several healthy, nutrient-dense foods as unhealthy; and is counterproductive to solve the major global food production challenges.[34]

The two researchers nonetheless share consensus that further study is required to understand the effect of food processing on human health:

The participants in this debate agree that food processing vitally affects human health, and that the extent of food processing significantly affects diet quality and health outcomes. They disagree on the significance of ultra-processing, as defined within the Nova food classification system.[35]

In 2022, the Scientific Advisory Committee on Nutrition (SACN) reviewed scientific literature to consider whether the British government should adopt a position on ultra-processed food and recommended further research, scheduling a review on its position for June 2024.[36]

See also

References

  1. ^ Monteiro, Carlos (2010). "The big issue is ultra-processing". World Nutrition. 1 (6): 237–269. ISSN 2041-9775.
  2. ^ Monteiro, Carlos (2011). "The big issue is ultra-processing. Why bread, hot dogs – and margarine – are ultra-processed". World Nutrition. 2 (10): 534–549. ISSN 2041-9775.
  3. ^ a b Monteiro, Carlos A.; Cannon, Geoffrey; Levy, Renata B; Moubarac, Jean-Claude; Louzada, Maria L. C.; Rauber, Fernanda; Khandpur, Neha; Cediel, Gustavo; Neri, Daniela; Martinez-Steele, Euridice; Baraldi, Larissa G.; Jaime, Patricia C. (2019). "Ultra-processed foods: what they are and how to identify them". Public Health Nutrition. 22 (5): 936–941. doi:10.1017/S1368980018003762. ISSN 1368-9800. PMC 10260459. PMID 30744710.
  4. ^ Touvier, Mathilde; Louzada, Maria Laura da Costa; Mozaffarian, Dariush; Baker, Phillip; Juul, Filippa; Srour, Bernard (2023-10-09). "Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait". BMJ. 383: e075294. doi:10.1136/bmj-2023-075294. ISSN 1756-1833. PMC 10561017. PMID 37813465.
  5. ^ Fardet, Anthony; Rock, Edmond (2019-11-01). "Ultra-processed foods: A new holistic paradigm?". Trends in Food Science & Technology. 93: 174–184. doi:10.1016/j.tifs.2019.09.016. ISSN 0924-2244. S2CID 203896042.
  6. ^ Moubarac, Jean-Claude; Parra, Diana C.; Cannon, Geoffrey; Monteiro, Carlos A. (2014-06-01). "Food Classification Systems Based on Food Processing: Significance and Implications for Policies and Actions: A Systematic Literature Review and Assessment". Current Obesity Reports. 3 (2): 256–272. doi:10.1007/s13679-014-0092-0. ISSN 2162-4968.
  7. ^ a b Pagliai, G.; Dinu, M.; Madarena, M. P.; Bonaccio, M.; Iacoviello, L.; Sofi, F. (2021-02-14). "Consumption of ultra-processed foods and health status: a systematic review and meta-analysis". British Journal of Nutrition. 125 (3): 308–318. doi:10.1017/S0007114520002688. ISSN 0007-1145. PMC 7844609. PMID 32792031.
  8. ^ a b Leite, Fernanda Helena Marrocos; Khandpur, Neha; Andrade, Giovanna Calixto; Anastasiou, Kim; Baker, Phillip; Lawrence, Mark; Monteiro, Carlos Augusto (2022-03-01). "Ultra-processed foods should be central to global food systems dialogue and action on biodiversity". BMJ Global Health. 7 (3): e008269. doi:10.1136/bmjgh-2021-008269. ISSN 2059-7908. PMC 8895941. PMID 35346976.
  9. ^ a b Gibney, Michael J (2019-02-01). "Ultra-processed foods: Definitions and policy issues". Current Developments in Nutrition. 3 (2): nzy077. doi:10.1093/cdn/nzy077. PMC 6389637. PMID 30820487.
  10. ^ Monteiro, Carlos A. (2009-05-01). "Nutrition and health. The issue is not food, nor nutrients, so much as processing". Public Health Nutrition. 12 (5): 729–731. doi:10.1017/S1368980009005291. ISSN 1475-2727. PMID 19366466. S2CID 42136316.
  11. ^ Hässig, Alenica; Hartmann, Christina; Sanchez-Siles, Luisma; Siegrist, Michael (2023-08-01). "Perceived degree of food processing as a cue for perceived healthiness: The NOVA system mirrors consumers' perceptions". Food Quality and Preference. 110: 104944. doi:10.1016/j.foodqual.2023.104944. ISSN 0950-3293. S2CID 259941132.
  12. ^ Ares, Gastón; Vidal, Leticia; Allegue, Gimena; Giménez, Ana; Bandeira, Elisa; Moratorio, Ximena; Molina, Verónika; Curutchet, María Rosa (2016-10-01). "Consumers' conceptualization of ultra-processed foods". Appetite. 105: 611–617. doi:10.1016/j.appet.2016.06.028. ISSN 0195-6663. PMID 27349706. S2CID 3554621.
  13. ^ Visioli, Francesco; Marangoni, Franca; Fogliano, Vincenzo; Rio, Daniele Del; Martinez, J. Alfredo; Kuhnle, Gunter; Buttriss, Judith; Ribeiro, Hugo Da Costa; Bier, Dennis; Poli, Andrea (2022-06-22). "The ultra-processed foods hypothesis: a product processed well beyond the basic ingredients in the package". Nutrition Research Reviews: 1–11. doi:10.1017/S0954422422000117. ISSN 0954-4224. PMID 35730561. S2CID 249923737.
  14. ^ Darmon, Nicole (2009-10-01). "The good, the bad, and the ultra-processed". Public Health Nutrition. 12 (10): 1967–1968. doi:10.1017/S1368980009991212. ISSN 1475-2727. PMID 19732488. S2CID 233340283.
  15. ^ Monteiro, Carlos Augusto; Levy, Renata Bertazzi; Claro, Rafael Moreira; de Castro, Inês Rugani Ribeiro; Cannon, Geoffrey (2010). "A new classification of foods based on the extent and purpose of their processing". Cadernos de Saúde Pública. 26 (11): 2039–2049. doi:10.1590/S0102-311X2010001100005. ISSN 0102-311X. PMID 21180977.
  16. ^ Martinez-Steele, Euridice; Khandpur, Neha; Batis, Carolina; Bes-Rastrollo, Maira; Bonaccio, Marialaura; Cediel, Gustavo; Huybrechts, Inge; Juul, Filippa; Levy, Renata B.; da Costa Louzada, Maria Laura; Machado, Priscila P.; Moubarac, Jean-Claude; Nansel, Tonja; Rauber, Fernanda; Srour, Bernard (2023-06-01). "Best practices for applying the Nova food classification system". Nature Food. 4 (6): 445–448. doi:10.1038/s43016-023-00779-w. ISSN 2662-1355. PMID 37264165. S2CID 259024679.
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  19. ^ Monteiro, C. A.; Moubarac, J.‐C.; Cannon, G.; Ng, S. W.; Popkin, B. (2013). "Ultra‐processed products are becoming dominant in the global food system". Obesity Reviews. 14 (S2): 21–28. doi:10.1111/obr.12107. ISSN 1467-7881. PMID 24102801. S2CID 13735684.
  20. ^ Monteiro, Carlos Augusto; Cannon, Geoffrey; Moubarac, Jean-Claude; Levy, Renata Bertazzi; Louzada, Maria Laura C; Jaime, Patrícia Constante (2018). "The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing". Public Health Nutrition. 21 (1): 5–17. doi:10.1017/S1368980017000234. ISSN 1368-9800. PMC 10261019. PMID 28322183.
  21. ^ Delpino, Felipe Mendes; Figueiredo, Lílian Munhoz; Bielemann, Renata Moraes; da Silva, Bruna Gonçalves Cordeiro; dos Santos, Francine Silva; Mintem, Gicele Costa; Flores, Thaynã Ramos; Arcêncio, Ricardo Alexandre; Nunes, Bruno Pereira (2022-08-10). "Ultra-processed food and risk of type 2 diabetes: a systematic review and meta-analysis of longitudinal studies". International Journal of Epidemiology. 51 (4): 1120–1141. doi:10.1093/ije/dyab247. ISSN 0300-5771. PMID 34904160.
  22. ^ Isaksen, Irja Minde; Dankel, Simon Nitter (2023-06-01). "Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis". Clinical Nutrition. 42 (6): 919–928. doi:10.1016/j.clnu.2023.03.018. ISSN 0261-5614. PMID 37087831. S2CID 257872002.
  23. ^ Seferidi, Paraskevi; Scrinis, Gyorgy; Huybrechts, Inge; Woods, Jeremy; Vineis, Paolo; Millett, Christopher (2020-10-01). "The neglected environmental impacts of ultra-processed foods". The Lancet Planetary Health. 4 (10): e437–e438. doi:10.1016/S2542-5196(20)30177-7. ISSN 2542-5196. PMID 33038314. S2CID 222280757.
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  25. ^ "Guías Alimentarias para la Población Uruguaya". Montevideo: Ministerio de Salud del Uruguay. 2016.
  26. ^ Guías Alimentarias para la Población Peruana (Report). Lima: Ministerio de Salud del Perú. 2018.
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