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== Innovations and substantial contributions to science == |
== Innovations and substantial contributions to science == |
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* Identification of sRAGE, the soluble form of the [[RAGE_(receptor)|receptor for advanced glycation endproducts]], as related to [[atherosclerosis]],<ref>{{cite journal |pmid=15731496}}</ref> [[dementia]],<ref>{{cite journal |pmid=16286548}}</ref> and [[longevity]].<ref>{{cite journal |pmid=16866696}}</ref> |
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* Identification of sRAGE, the soluble form of the [[RAGE_(receptor)|receptor for advanced glycation endproducts]], as related to [[atherosclerosis]],<ref>Falcone C, Emanuele E, D’Angelo A, Buzzi MP, Belvito C, Cuccia M, Geroldi D. Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men. Arterioscl Thromb Vasc Biol, 25: 1032–1037, 2005. [http://www.ncbi.nlm.nih.gov/pubmed/15731496?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PMID: 15731496]</ref> [[dementia]],<ref>Emanuele E, D’Angelo A, Tomaino C, Binetti G, Ghidoni R, Politi P, Bernardi L, Maletta R, Bruni AC, Geroldi D. Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia. Arch Neurol, 62: 1734–1736, 2005. [http://www.ncbi.nlm.nih.gov/pubmed/16286548 PMID: 16286548]</ref> and [[longevity]].<ref>Geroldi D, Falcone C, Minoretti P, Emanuele E, Arra M, D’Angelo A. High levels of soluble receptor for advanced glycation end products may be a marker of extreme longevity in humans. J Am Geriatr Soc, 54: 1149–1150, 2006. [http://www.ncbi.nlm.nih.gov/pubmed/16866696 PMID: 16866696]</ref> |
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* Identification of the [[neurotrophin]] [[nerve growth factor]] (NGF) as a biochemical mediator of falling in [[love]] in humans.<ref> |
* Identification of the [[neurotrophin]] [[nerve growth factor]] (NGF) as a biochemical mediator of falling in [[love]] in humans.<ref>{{cite journal |pmid=16289361}}</ref> |
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* Genetic dissection of human [[mating]] system and [[love styles]].<ref> |
* Genetic dissection of human [[mating]] system and [[love styles]].<ref>{{cite journal |pmid=16406690}}</ref><ref>{{cite journal |pmid=18063936}}</ref> |
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* Identification of [[Biomarker_(medicine)|biochemical markers]] of [[autism]].<ref>{{cite journal |pmid=17101220}}</ref><ref>{{cite journal |pmid=17174726}}</ref> |
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* Identification of [[Biomarker_(medicine)|biochemical markers]] of [[autism]].<ref>Boso M, Emanuele E, Politi P, Minoretti P, Arra M, Ucelli di Nemi S, Barale F. Alterations of circulating endogenous secretory RAGE and S100A9 levels indicating dysfunction of the AGE-RAGE axis in autism. Neurosci Lett, 410: 169–173, 2006. [http://www.ncbi.nlm.nih.gov/pubmed/17101220 PMID: 17101220]</ref><ref>Boso M, Emanuele E, Politi P, Pace A, Arra M, Ucelli di Nemi S, Barale F. Reduced plasma apelin levels in patients with autistic spectrum disorder. Arch Med Res, 38: 70–74, 2007. [http://www.ncbi.nlm.nih.gov/pubmed/17174726 PMID: 17174726]</ref> |
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* [[Genetics]] of sporadic [[Alzheimer's disease]].<ref>{{cite journal |pmid=19664850}}</ref><ref>{{cite journal |pmid=17090974}}</ref> |
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* [[Genetics]] of sporadic [[Alzheimer's disease]].<ref>Emanuele E, Lista S, Guidoni R, Binetti G, Cereda C, Benussi L, Maletta R, Bruni AC, Politi P. Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer’s disease. Neurobiol Aging, in press. [http://www.ncbi.nlm.nih.gov/pubmed/19664850?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PMID: 19664850]</ref><ref>Arra M, Emanuele E, Martinelli V, Minoretti P, Bertona M, Geroldi D. The M694V variant of the familial Mediterranean fever gene is associated with sporadic early-onset Alzheimer's disease in an Italian population sample. Dement Geriatr Cogn Disord, 23: 55–59, 2006. [http://www.ncbi.nlm.nih.gov/pubmed/17090974 PMID: 17090974]</ref> |
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* Identification of [[Biomarker_(medicine)|biochemical markers]] related to [[aggressive behaviour]] in [[domestic animals]].<ref> |
* Identification of [[Biomarker_(medicine)|biochemical markers]] related to [[aggressive behaviour]] in [[domestic animals]].<ref>{{cite journal |doi=10.1007/s10164-007-0079-3}}</ref><ref>{{cite journal |pmid=17891468}}</ref> |
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* Role of [[serotonin]] and [[omega-3 fatty acids]] in experimental [[neuroeconomics]].<ref>{{cite journal |pmid=18448251}}</ref><ref>{{cite journal |doi=10.1016/j.bihy.2008.10.010}}</ref><ref>{{cite journal |pmid=18940191}}</ref> |
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* Role of [[serotonin]] and [[omega-3 fatty acids]] in experimental [[neuroeconomics]].<ref>Emanuele E, Brondino N, Bertona M, Re S, Geroldi D. Relationship between platelet serotonin content and rejections of unfair offers in the ultimatum game. Neurosci Lett, 347: 158–161, 2008. [http://www.ncbi.nlm.nih.gov/pubmed/18448251 PMID: 18448251]</ref><ref>Emanuele E, Bertona M, Re S, Brondino N. Human economic and financial behavior: The serotonergic hypothesis. Biosci Hypotheses, 2: 109–110, 2009.</ref><ref>Emanuele E, Brondino N, Re S, Bertona M, Geroldi D. Serum omega-3 fatty acids are associated with ultimatum bargaining behaviour. Physiol Behav, 96: 180–183, 2009.[http://www.ncbi.nlm.nih.gov/pubmed/18940191 PMID: 18940191]</ref> |
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== References == |
== References == |
Revision as of 20:00, 25 August 2009
Enzo Emanuele | |
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Born | |
Nationality | Italian |
Alma mater | Pavia Medical School - University of Pavia |
Known for | Biomarker discovery, Interdisciplinary research |
Awards | Zdenek Klein Award for Human Ethology (2008) |
Scientific career | |
Fields | Clinical Pathology |
Enzo Emanuele born June 10, 1977, in Novara, Italy, is an Italian clinical pathologist well-known for his contributions in the study of biomarkers of psychiatric, neurological, and cardiovascular disorders. He is also renowned for his interdisciplinary research in the fields of biological psychology and neuroeconomics.
In 2002 graduated as MD from the University of Pavia, Pavia, Italy.
In 2008, he received the International Zdenek Klein Award for Human Ethology from the Charles University in Prague, Czech Republic.
Enzo Emanuele is Associate Editor of the journal Atherosclerosis.[1]
Innovations and substantial contributions to science
- Identification of sRAGE, the soluble form of the receptor for advanced glycation endproducts, as related to atherosclerosis,[2] dementia,[3] and longevity.[4]
- Identification of the neurotrophin nerve growth factor (NGF) as a biochemical mediator of falling in love in humans.[5]
- Genetic dissection of human mating system and love styles.[6][7]
- Identification of biochemical markers of autism.[8][9]
- Genetics of sporadic Alzheimer's disease.[10][11]
- Identification of biochemical markers related to aggressive behaviour in domestic animals.[12][13]
- Role of serotonin and omega-3 fatty acids in experimental neuroeconomics.[14][15][16]
References
- ^ "Associate Editors". European Atherosclerosis Society. Retrieved August 25, 2009.
- ^ . PMID 15731496.
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(help) - ^ . doi:10.1007/s10164-007-0079-3.
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(help) - ^ . PMID 18940191.
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