ATP5F1

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ATP5PB
Identifiers
AliasesATP5PB, PIG47, ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1, ATP synthase peripheral stalk-membrane subunit b, ATP5F1
External IDsOMIM: 603270 MGI: 1100495 HomoloGene: 1275 GeneCards: ATP5PB
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001688
NM_001002014
NM_001002015

NM_009725
NM_001304719

RefSeq (protein)

NP_001679

NP_001291648
NP_033855

Location (UCSC)Chr 1: 111.45 – 111.46 MbChr 3: 105.85 – 105.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
ATP-synt_B
atp synthase b subunit dimerization domain
Identifiers
SymbolATP-synt_B
PfamPF00430
Pfam clanCL0255
InterProIPR002146
SCOP21b9u / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

ATP synthase subunit b, mitochondrial is an enzyme that in humans is encoded by the ATP5F1 gene.[5][6]

Template:PBB Summary

The b subunits are part of the peripheral stalk that links the F1 and FO complexes together, and which acts as a stator to prevent certain subunits from rotating with the central rotary element. The peripheral stalk differs in subunit composition between mitochondrial, chloroplast and bacterial F-ATPases. In bacterial and chloroplast F-ATPases, the peripheral stalk is composed of one copy of the delta subunit (homologous to OSCP in mitochondria), and two copies of subunit b in bacteria, or one copy each of subunits b and b' in chloroplasts and photosynthetic bacteria.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116459Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000563Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Higuti T, Tsurumi C, Osaka F, Kawamura Y, Tsujita H, Yoshihara Y, Tani I, Tanaka K, Ichihara A (Sep 1991). "Molecular cloning of cDNA for the import precursor of human subunit B of H(+)-ATP synthase in mitochondria". Biochem Biophys Res Commun. 178 (3): 1014–20. doi:10.1016/0006-291X(91)90993-H. PMID 1831354.
  6. ^ "Entrez Gene: ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1".
  7. ^ Carbajo RJ, Kellas FA, Runswick MJ, Montgomery MG, Walker JE, Neuhaus D (August 2005). "Structure of the F1-binding domain of the stator of bovine F1Fo-ATPase and how it binds an alpha-subunit". J. Mol. Biol. 351 (4): 824–38. doi:10.1016/j.jmb.2005.06.012. PMID 16045926.

External links

Further reading

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This article incorporates text from the public domain Pfam and InterPro: IPR002146