Adipose triglyceride lipase

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Patatin-like phospholipase domain containing 2
Symbols PNPLA2 ; 1110001C14Rik; ATGL; PEDF-R; TTS-2.2; TTS2; iPLA2zeta
External IDs OMIM609059 MGI1914103 HomoloGene10687 GeneCards: PNPLA2 Gene
EC number
RNA expression pattern
PBB GE PNPLA2 212705 x at tn.png
PBB GE PNPLA2 39854 r at tn.png
More reference expression data
Species Human Mouse
Entrez 57104 66853
Ensembl ENSG00000177666 ENSMUSG00000025509
UniProt Q96AD5 Q8BJ56
RefSeq (mRNA) NM_020376 NM_001163689
RefSeq (protein) NP_065109 NP_001157161
Location (UCSC) Chr 11:
0.82 – 0.83 Mb
Chr 7:
141.46 – 141.46 Mb
PubMed search [1] [2]

Adipose triglyceride lipase also known as patatin-like phospholipase domain-containing protein 2 is an enzyme that in humans is encoded by the PNPLA2 gene.[1][2][3][4]


  1. ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  2. ^ Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ (Aug 2006). "Characterization of the human patatin-like phospholipase family". J Lipid Res 47 (9): 1940–9. doi:10.1194/jlr.M600185-JLR200. PMID 16799181. 
  3. ^ Kienesberger PC, Oberer M, Lass A, Zechner R (Apr 2009). "Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions". J Lipid Res. 50 Suppl (Supplement): S63–8. doi:10.1194/jlr.R800082-JLR200. PMC 2674697. PMID 19029121. 
  4. ^ "Entrez Gene: PNPLA2 patatin-like phospholipase domain containing 2". 

Further reading[edit]