Robbia was the son of Marco della Robbia. Andrea della Robbia's uncle, Luca della Robbia, popularized the use of glazed terra-cotta for sculpture. "The medium gained great popularity in fifteenth-century Florence and became a specialty of the della Robbia family studio, which was directed by Andrea after Luca, his uncle, died. Altarpieces made of glazed terra-cotta were more colorful, less expensive, and easier to transport than similar sculptures in marble".
Born in Florence, Robbia was the most important artist of ceramic glaze of the times. His workshop was carried on by his son Giovanni after his death.