Murena completed a church of Monte Morcino at Perugia for the Olivetan monks. He designed the tabernacle for the Cathedral of Terni. At Foligno, he designed the church of the Holy Trinity. In Rome, Murena constructed the Zampai chapel and its funereal monuments, all found in Sant'Antonio dei Portoghesi. His work has been the subject of or discussed in many books on Baroque architecture in Italy.