Destelbergen (Dutch pronunciation: [ˌd̪ɛs̪t̪ə̪l̪ˈbɛrɣ̟ə(n̪)]) is a municipality located in the Belgian province of East Flanders. The municipality comprises the towns of Destelbergen proper and Heusden and was created on January 1, 1977 by the fusion of these two municipalities. Its western border touches the municipality of Ghent and Melle and is formed by an ancient silted up branch of the river Scheldt.
Curiosities worth seeing are the many residential castles, a Gaulish farmhouse, and the Damvallei nature reserve.
On January 1, 2011 Destelbergen had a total population of 17,636. The total area is 26.56 km² which gives a population density of 664 inhabitants per km².