EGOT (gene)

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Eosinophil granule ontogeny transcript (non-protein coding)
Symbols EGOT ; EGO; NCRNA00190
External IDs OMIM611662 GeneCards: EGOT Gene
Species Human Mouse
Entrez 100126791 n/a
Ensembl ENSG00000235947 n/a
UniProt n/a n/a
RefSeq (mRNA) NR_004428 n/a
RefSeq (protein) n/a n/a
Location (UCSC) Chr 3:
4.79 – 4.79 Mb
PubMed search [1] n/a

EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript (non-protein coding),[1] is a human gene at 3p26.1 encoding a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 (ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression.[1] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals.[2]

†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature.[3]