Irons's career in journalism began at the Daily Mail, where the editor assigned her to the beauty page even though she herself had never worn makeup. She was ultimately fired for "looking unfashionable". At the Evening Standard she edited the "women's interest" pages, but when World War II broke out she informed the news editor "From now on I'm working for you." Though General Montgomery objected to women reporters on the battlefield, she gained the support of French General Jean de Lattre de Tassigny and became one of the first journalists to reach liberated Paris. She was the first woman journalist to reach Hitler's Eagle's Nest after its capture; after climbing there through the snow she helped herself to a bottle of Hitler's "excellent Rhine wine".
Irons travelled to the United States in 1952 to cover the presidential election and stayed on afterward, settling near Brewster, New York. In 1954 she broke a news embargo on the overthrow of Guatemalan President Jacobo Arbenz Guzmán by hiring a mule to take her to Chiquimula while other journalists, forbidden to cross the border, waited in a bar in Honduras. She became the first reporter to reach the headquarters of the Provisional Government; a reporter for a rival paper received a telegram from his editor ordering him to "offget arse onget donkey".
Irons's relationship with the writer Vita Sackville-West was well-known – months before her death, an Evening Standard headline identified her as the "war correspondent who broke Vita's heart" – but the romance was brief.
According to biographer Victoria Glendinning, in 1931 Irons went as editor of the Daily Mail women's page to interview Sackville-West at Sissinghurst where she was designing and shaping the famous gardens. Sackville-West was married to Harold Nicolson (and had already had several extra-marital affairs including Violet Trefusis), while Irons was involved with Olive Rinder. As if this were not complex enough, Rinder also became a lover of Sackville-West, forming a menage-a-trois during 1932 that ended when Irons met a fellow journalist, Joy McSweeney.
In 1935, Irons won the Royal Humane Society's Stanhope Gold Medal "for the bravest deed of 1935". She "rescued a woman from drowning under very courageous circumstances at Tresaith Beach, Cardiganshire." It was the first time the medal had been awarded to a woman.
- Glendinning, Victoria. Vita: The Life of V. Sackville-West. Weidenfeld & Nicolson, 1983.
- Watson, Molly (5 January 2000). "Standard War Correspondent Who Broke Vita's Heart". Evening Standard (London). Retrieved 5 February 2007.
- "Obituaries". Evelyn Graham Irons, 99, War Correspondent. Associated Press. 1 May 2000. Retrieved 15 January 2012.
- Chambers, Deborah; Linda Steiner and Carole Fleming (2004). Women and Journalism. Routledge. p. 204. Retrieved 9 March 2012.
- "Edinburgh Gazette" (PDF). Joseph Jones Irons. Edinburgh Gazette. 26 November 1929. p. 1483. Retrieved 15 January 2012.
- Lewis, Paul (30 April 2000). "Obituaries". Evelyn Irons, War Reporter, Is Dead at 99. New York Times. Retrieved 15 January 2012.
- Brenner, Felix (25 April 2000). "Obituary: Evelyn Irons". The Independent (London). Retrieved 5 February 2007.
- "Evelyn Irons". Times (London). 11 May 2000. p. 25. ProQuest document ID 53720412.
- Glendinning, 1983.
- "Outside the Gates" (PDF). Stanhope Gold Medal. The British Journal of Nursing. August 1936. p. 222. Retrieved 15 January 2012.