Jump to content

File:Influence of pigmentation on skin cancer risk.png

Page contents not supported in other languages.
This is a file from the Wikimedia Commons
From Wikipedia, the free encyclopedia

Original file (1,276 × 490 pixels, file size: 260 KB, MIME type: image/png)

This diagram image could be re-created using vector graphics as an SVG file. This has several advantages; see Commons:Media for cleanup for more information. If an SVG form of this image is available, please upload it and afterwards replace this template with {{vector version available|new image name}}.


It is recommended to name the SVG file “Influence of pigmentation on skin cancer risk.svg”—then the template Vector version available (or Vva) does not need the new image name parameter.

Summary

Description
English: Influence of pigmentation on skin cancer risk. Fair-skinned individuals with low levels of melanin in the epidermis display a UV sensitive phenotype, tending to burn rather than tan, after UV exposure. Recent data suggest that mutations that contribute to fair complexion and tanning impairment, specifically signaling defects in the melanocortin 1 receptor (MC1R), may also be associated with less efficient DNA repair in melanocytes. MC1R-defective individuals not only suffer higher realized doses of UV radiation because their skin is less able to block UV photons, but they may also accumulate more mutations from UV exposure because of defective DNA repair.
Date Published: 7 June 2013
Source John D’Orazio et al. "UV Radiation and the Skin" Int. J. Mol. Sci. 2013, 14(6), 12222-12248; doi:10.3390/ijms140612222 http://www.mdpi.com/1422-0067/14/6/12222/htm
Author John D’Orazio, Stuart Jarrett, Alexandra Amaro-Ortiz and Timothy Scott

Licensing

w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 3.0 Unported license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

Captions

Fitzpatrick Scale

Items portrayed in this file

depicts

measurement scale

media type

image/png

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current04:56, 18 April 2021Thumbnail for version as of 04:56, 18 April 20211,276 × 490 (260 KB)JPxGfix strange, extraterrestrial eyes
00:13, 18 January 2018Thumbnail for version as of 00:13, 18 January 20181,276 × 490 (273 KB)ErulasReverted to version as of 00:07, 18 January 2018 (UTC)
00:13, 18 January 2018Thumbnail for version as of 00:13, 18 January 20182,754 × 1,054 (8.31 MB)ErulasAccidentally uploaded the original rather than the edited file
00:07, 18 January 2018Thumbnail for version as of 00:07, 18 January 20181,276 × 490 (273 KB)ErulasRemoved lazy and inaccurate racial categories that accompanied the skin tone types. Asians and Native Americans were glossed over as homogeneous categories even though their skin tones span nearly the entire Fitzpatrick scale. Austronesians were crudel...
20:09, 23 June 2016Thumbnail for version as of 20:09, 23 June 20162,754 × 1,447 (555 KB)Was a bee{{Information |Description={{en|1=Influence of pigmentation on skin cancer risk. Fair-skinned individuals with low levels of melanin in the epidermis display a UV sensitive phenotype, tending to burn rather than tan, after UV exposure. Recent data sugg...

The following 3 pages use this file:

Global file usage

The following other wikis use this file:

Metadata

This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.

If the file has been modified from its original state, some details may not fully reflect the modified file.

Retrieved from "https://en.wikipedia.org/wiki/File:Influence_of_pigmentation_on_skin_cancer_risk.png"