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Rho guanine nucleotide exchange factor (GEF) 25
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ARHGEF25 ; GEFT; p63RhoGEF
External IDs OMIM610215 MGI1277173 HomoloGene32691 GeneCards: ARHGEF25 Gene
Species Human Mouse
Entrez 115557 52666
Ensembl ENSG00000240771 ENSMUSG00000019467
UniProt Q86VW2 Q9CWR0
RefSeq (mRNA) NM_001111270 NM_001166413
RefSeq (protein) NP_001104740 NP_001159885
Location (UCSC) Chr 12:
58 – 58.01 Mb
Chr 10:
127.18 – 127.19 Mb
PubMed search [1] [2]

RAC/CDC42 exchange factor, also known as GEFT, is a human gene.[1]


GEFT has been shown to interact with RHOA.[2]


  1. ^ "Entrez Gene: GEFT RAC/CDC42 exchange factor". 
  2. ^ Lutz, Susanne; Freichel-Blomquist Andrea, Rümenapp Ulrich, Schmidt Martina, Jakobs Karl H, Wieland Thomas (May 2004). "p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene". Naunyn Schmiedebergs Arch. Pharmacol. (Germany) 369 (5): 540–6. doi:10.1007/s00210-004-0926-5. ISSN 0028-1298. PMID 15069594. 

Further reading[edit]