HYOU1

HYOU1
Identifiers
Aliases	HYOU1, GRP-170, Grp170, HSP12A, ORP-150, ORP150, hypoxia up-regulated 1, IMD59
External IDs	OMIM: 601746 MGI: 108030 HomoloGene: 4658 GeneCards: HYOU1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	119,057,227 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	44,303,666 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; body of pancreas; ; anterior pituitary; ; right lobe of thyroid gland; ; stromal cell of endometrium; ; left lobe of thyroid gland; ; appendix; ; right lobe of liver; ; bone marrow cells; ; hypothalamus;
	Top expressed in
	spermatocyte; ; otic placode; ; saccule; ; spermatid; ; supraoptic nucleus; ; pyloric antrum; ; ciliary body; ; submandibular gland; ; internal carotid artery; ; islet of Langerhans;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; chaperone binding; ATP binding; protein binding;
Cellular component	endocytic vesicle lumen; endoplasmic reticulum lumen; membrane; focal adhesion; smooth endoplasmic reticulum; endoplasmic reticulum chaperone complex; extracellular region; endoplasmic reticulum; extracellular exosome;
Biological process	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway; negative regulation of apoptotic process; receptor-mediated endocytosis; response to endoplasmic reticulum stress; endoplasmic reticulum to Golgi vesicle-mediated transport; IRE1-mediated unfolded protein response; response to ischemia; cellular response to hypoxia; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10525
	12282
	ENSG00000280682; ENSG00000149428
	ENSMUSG00000032115
	Q9Y4L1; Q9BST8
	Q9JKR6
	NM_001130991; NM_006389
	NM_021395
	NP_001124463; NP_006380
	NP_067370
	Wikidata
View/Edit Human	View/Edit Mouse

Hypoxia up-regulated protein 1 is a protein that in humans is encoded by the HYOU1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c ENSG00000149428 GRCh38: Ensembl release 89: ENSG00000280682, ENSG00000149428 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032115 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ikeda J, Kaneda S, Kuwabara K, Ogawa S, Kobayashi T, Matsumoto M, Yura T, Yanagi H (Feb 1997). "Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein, ORP150". Biochem Biophys Res Commun. 230 (1): 94–9. doi:10.1006/bbrc.1996.5890. PMID 9020069.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Ozawa K, Kuwabara K, Tamatani M, Takatsuji K, Tsukamoto Y, Kaneda S, Yanagi H, Stern DM, Eguchi Y, Tsujimoto Y, Ogawa S, Tohyama M (Mar 1999). "150-kDa oxygen-regulated protein (ORP150) suppresses hypoxia-induced apoptotic cell death". J Biol Chem. 274 (10): 6397–404. doi:10.1074/jbc.274.10.6397. PMID 10037731.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: HYOU1 hypoxia up-regulated 1".

References

Further reading