Nonpuerperal mastitis

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The term nonpuerperal mastitis describes inflammatory lesions of the breast occurring unrelated to pregnancy and breastfeeding.

It is sometimes equated with duct ectasia, but other forms can be described.[1]


Duct ectasia[edit]

Duct ectasia - literally (lactiferous) duct widening is a very common and thus rather unspecific finding, increasing with age.

Subareolar abscess[edit]

Main article: Subareolar abscess

Also called Zuska's disease (only nonpuerperal case), is a frequently aseptic inflammation and has been associated with squamous metaplasia of the lactiferous ducts.

Granulomatous mastitis[edit]

Characteristic for granulomatous mastitis are multinucleated giant cells and epithelioid histiocytes around lobules. Often minor ductal and periductal inflammation is present. The lesion is in some cases very difficult to distinguish from breast cancer.

Comedo mastitis[edit]

Comedo mastitis is a very rare form similar to granulomatous mastitis but with tissue necrosis. Because it is so rare it may be sometimes confused with comedo carcinoma of the breast although the conditions appear to be completely unrelated.


  1. ^ Peters F, Schuth W (March 1989). "Hyperprolactinemia and nonpuerperal mastitis (duct ectasia)". JAMA 261 (11): 1618–20. doi:10.1001/jama.1989.03420110094030. PMID 2918655.