Omega-hydroxydecanoate dehydrogenase
omega-hydroxydecanoate dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.66 | ||||||||
CAS no. | 9028-65-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an omega-hydroxydecanoate dehydrogenase (EC 1.1.1.66) is an enzyme that catalyzes the chemical reaction
- 10-hydroxydecanoate + NAD+ ⇌ 10-oxodecanoate + NADH + H+
Thus, the two substrates of this enzyme are 10-hydroxydecanoate and NAD+, whereas its 3 products are 10-oxodecanoate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD+ 10-oxidoreductase.
References
- Kamei S, Wakabayashi K and Shimazono M (Tokyo). "omega-Oxidation of fatty acids in vitro. II. omega-Hydroxy fatty acid-NAD oxidoreductase". J. Biochem.: 72–76. PMID 14202238.
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(help) - Mitz MA and Henrikson RL (1961). "Omega hydroxy fatty acid dehydrogenase". Biochim. Biophys. Acta. 46: 45–50. doi:10.1016/0006-3002(61)90644-8. PMID 13771448.