The disposal program involved loading old munitions onto ships which were then slated to be scuttled once they were up to 250 miles off shore. While most of the sinkings involved ships loaded with conventional weapons, there were four which involved chemical weapons. The chemical weapons disposal site was a three-mile (5 km) area of the Atlantic Ocean between the coast of the U.S. state of Florida and the Bahamas. The CHASE program was pre-dated by United States Army disposal of 8000 tons of mustard and lewisite chemical warfare gas aboard the scuttled SS William C. Ralston in April 1958. These ships were sunk by having Explosive Ordnance Demolition (EOD) teams open seacocks on the ship after arrival at the disposal point. The typical Liberty ship sank about three hours after the seacocks were opened.
The mothballed C-3 Liberty ship John F. Shafroth was taken from the National Defense Reserve Fleet at Suisun Bay and towed to the Concord Naval Weapons Station for stripping and loading. A major fraction of the munitions in CHASE 1 was Bofors 40 mm gun ammunition from the Naval Ammunition Depot at Hastings, Nebraska. CHASE 1 also included bombs, torpedo warheads, naval mines, cartridges, projectiles, fuzes, detonators, boosters, overage UGM-27 Polaris motors, and a quantity of contaminated cake mix an army court had ordered dumped at sea. Shafroth was sunk 47 miles off San Francisco on 23 July 1964 with 9799 tons of munitions.
Village was loaded with 7348 short tons of munitions at the Naval Weapons Station Earle and towed to a deep-water dump site on 17 September 1964. There were three large and unexpected detonations five minutes after Village slipped beneath the surface. An oil slick and some debris appeared on the surface. The explosion registered on seismic equipment all over the world. Inquiries were received regarding seismic activity off the east coast of the United States, and the Office of Naval Research and Advanced Research Projects Agency expressed interest in measuring the differences between seismic shocks and underwater explosive detonations to detect underwater nuclear detonations then banned by treaty.
Coastal Mariner was loaded with 4040 short tons of munitions at the Naval Weapons Station Earle. The munitions included 512 tons of actual explosives. Four SOFAR bombs were packed in the explosives cargo hold with booster charges of 500 pounds of TNT to detonate the cargo at a depth of 1000 feet (300 meters). The United States Coast Guard issued a notice to mariners and the United States Department of Fish and Wildlife and the United States Bureau of Commercial Fisheries sent observers. The explosives detonated seventeen seconds after Coastal Mariner slipped below the surface on 14 July 1965. The detonation created a 600-foot (200 meter) water spout, but was not deep enough to be recorded on seismic instruments.
Santiago Iglesias was loaded with 8715 tons of munitions at the Naval Weapons Station Earle, rigged for detonation at 1000 feet (300 meters), and detonated 31 seconds after sinking on 16 September 1965.
Isaac Van Zandt was loaded with 8000 tons of munitions (including 400 tons of high explosives) at the Naval Base Kitsap and rigged for detonation at 4000 feet (1.2 kilometers). On 23 May 1966 the tow cable parted en route to the planned disposal area. Navy tugs USS Tatnuck (ATA-195) and USS Koka (ATA-185) recovered the tow within six hours, but the location of sinking was changed by the delay.
Eric C. Gibson was sunk on 15 June 1967.
CHASE 10 dumped 3,000 tons of United States Army nerve agent filled rockets encased in concrete vaults. Public controversy delayed CHASE 10 disposal until August 1970. Public awareness of operation CHASE 10 was increased by mass media reporting following delivery of information from the Pentagon to the office of U.S. Representative Richard McCarthy in 1969. Both American television and print media followed the story with heavy coverage. In 1970, 58 separate reports were aired on the three major network news programs on NBC, ABC and CBS concerning Operation CHASE. Similarly, The New York Times included Operation CHASE coverage in 42 separate issues during 1970, 21 of those in the month of August.
CHASE 11 occurred in June 1968 and disposed of United States Army GB and VX, all sealed in tin containers.
CHASE 12, in August 1968, again disposed of United States Army mustard agent and was numerically (although not chronologically) the final mission to dispose of chemical weapons.
Operation CHASE was exposed to the public during a time when the army was under increasing public criticism, especially the army's Chemical Corps. CHASE was one of the incidents which led to the near-disbanding of the Chemical Corps in the aftermath of the Vietnam War. Concerns were raised over the program's effect on the ocean environment as well as the risk of chemical weapons washing up on shore. The concerns led to the Marine Protection, Research, and Sanctuaries Act of 1972, which prohibited future such missions.
- Kurak, Steve "Operation Chase" United States Naval Institute Proceedings September 1967 pp. 40-46
- "Chemical Stockpile Disposal Program. Chemical Weapons Movement History Compilation, William R. Brankowitz, 12 JUNE 1987". Retrieved 26 July 2013.
- Pike, John. "Operation CHASE", 27 April 2005, Globalsecurity.org. Retrieved 26 November 2007.
- Mauroni, Al. "The US Army Chemical Corps: Past, Present, and Future", Army Historical Foundation. Retrieved 26 November 2007.
- Wagner, Travis. "Hazardous Waste: Evolution of a National Environmental Problem", (Project Muse), Journal of Policy History, 16.4 (2004) pp. 306-331. Retrieved 26 November 2007.
- Kraft, James C. "The Last Triple Expander" United States Naval Institute Proceedings February 1977 p. 67