Pancrelipase is a mixture of porcine-derived pancreatic amylase, pancreatic lipase, and chymotrypsin.
Amylase, pancreatic lipase, and chymotrypsin (a kind of protease) are digestive enzymes normally produced by the pancreas.
Pancrelipase is used in the treatment of some digestive disorders, primarily exocrine pancreatic insufficiency, which can result from cystic fibrosis, chronic pancreatitis, and after pancreatectomy.
Pancrelipase is similar to the drug pancreatin, but has an elevated content of lipase.
Pancrelipase is available as hard capsules filled with gastro-resistant granules.