Pancrelipase
| Clinical data | |
|---|---|
| AHFS/Drugs.com | monograph |
| MedlinePlus | a604035 |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | Oral |
| Identifiers | |
| CAS number | 53608-75-6  |
| ATC code | A09AA02 |
| DrugBank | DB00085 |
| UNII | FQ3DRG0N5K |
| Chemical data | |
| Formula | C5850H8902N1606O1739S49 |
| Mol. mass | 131 kDa |
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Pancrelipase is a form of enzyme therapy for the treatment of various digestive disorders, primarily exocrine pancreatic insufficiency. It is a mixture of three digestive enzymes, amylase, trypsin, and lipase, which are normally produced by the pancreas. Pancrelipase is a form of pancreatin having a elevated content of lipase.
Contents |
[edit] Use
Pancrelipase is used by patients suffering from cystic fibrosis, chronic pancreatitis and after pancreatectomy.
Brand names for Pancrelipase include Creon, Pancrease, Ultrase, Mezym and Ozym.
[edit] Creon
Creon is a Pancrelipase manufactured and produce by Abbott Laboratories. Its available in different packaging ie Creon 5, 10 or 20.
Creon 10,000 mini-microspeheres (delayed release capsules) is available in China, Singapore, Malaysia and Thailand with enzyme contains lipase 10,000 u, amylase 8,000 u, protease 600 u.[1]
Its main indication is for patients with pancretic exocrine insufficiency ie, cystic fibrosis, chronic pancreatitis, pancreatectomy, pancreatic cancer and gastrotectomy.
[edit] References
- ^ "Creon 10000: Drug information, CME and news". MIMS.com. http://www.mims.com/Creon%2010000.html. Retrieved 2011-11-06.
[edit] External links
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