RHOBTB1

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Rho-related BTB domain containing 1
Identifiers
Symbols RHOBTB1 ; KIAA0740; MGC33059; MGC33841
External IDs OMIM607351 MGI1916538 HomoloGene8892 GeneCards: RHOBTB1 Gene
RNA expression pattern
PBB GE RHOBTB1 212651 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9886 69288
Ensembl ENSG00000072422 ENSMUSG00000019944
UniProt O94844 Q9DAK3
RefSeq (mRNA) NM_001242359 NM_001081347
RefSeq (protein) NP_001229288 NP_001074816
Location (UCSC) Chr 10:
62.63 – 62.76 Mb
Chr 10:
69.15 – 69.29 Mb
PubMed search [1] [2]

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene.[1][2]

The protein encoded by this gene belongs to the Rho family of the Ras superfamily of small GTPases. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.[2]

References[edit]

  1. ^ Rivero F, Dislich H, Glockner G, Noegel AA (Mar 2001). "The Dictyostelium discoideum family of Rho-related proteins". Nucleic Acids Res 29 (5): 1068–79. doi:10.1093/nar/29.5.1068. PMC 29714. PMID 11222756. 
  2. ^ a b "Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1". 

Further reading[edit]