Sally Quinn was born in Savannah, Georgia, to Lt. General William Wilson "Buffalo Bill" Quinn (November 1, 1907–September 11, 2000) and his wife, Sara Bette Williams, (January 27, 1918–September 26, 2004). Both are buried at Arlington National Cemetery. Quinn has two siblings—Donna of Oakland, California, and William Jr. of Phoenix, Arizona.
Her father was an infantry officer who also served as an intelligence officer and played a key role in the transition of the United States' intelligence service from the Office of Strategic Services (OSS) to the Central Intelligence Agency (CIA). As a Colonel in World War II, he helped coordinate the invasion of southern France in 1944 and captured Hermann Göring. Though he was not present, his regiment liberated Dachau concentration camp; he arrived the next day, when he heard the news. From 1964 to 1966, he commanded the 7th Army in Germany. Quinn wrote about his career in an autobiography, Buffalo Bill Remembers.
For many years, the Quinns lived on Connecticut Avenue N.W., Washington, D.C., where Bette Quinn was known for her cooking and entertaining. Sally Quinn reports in CC Goldwater's HBO film Mr. Conservative that Senator Barry Goldwater spent much time with the Quinns, often staying at their home, since his wife decided to remain in Arizona rather than D.C. while Congress was in session.
Quinn graduated from Smith College in 1963.
Quinn is the third wife of Benjamin C. Bradlee, her former boss at The Washington Post. Quinn and Bradlee have one child, Quinn Bradlee, born in 1982 when she was 41 and Bradlee was 61. In 2009, they appeared with Quinn Bradlee on the Charlie Rose show on PBS and spoke of Quinn being born with velo-cardio-facial syndrome, also known as 22q11.2 deletion and Shprintzen syndrome (named after Dr. Robert Shprintzen who first identified the disorder in 1978 and who also diagnosed Quinn Bradlee). Quinn wrote of Quinn's learning disabilities and attendance at special schools in a 2006 blog article "What My Son Taught Me About God."
Newspaper journalism 
A Savannah, Georgia, native and Smith College graduate, Quinn began at The Washington Post with very little experience: reportedly called by Ben Bradlee after a report of her pajama party in celebration of the election to Congress of Barry Goldwater, Jr., the job interview included the following exchange.
"Can you show me something you've written?" asked Managing Editor Benjamin Bradlee. "I've never written anything," admitted Quinn. Pause. "Well," said Bradlee, "nobody's perfect." 
However, she soon demonstrated, as a reporter for the paper's style section, a talent for drawing out the subjects of her interviews and profiles. Henry Kissinger said, "[The Post reporter] Maxine Cheshire makes you want to commit murder. Sally Quinn makes you want to commit suicide." A notable incident of her career was her claim that Zbigniew Brzezinski, then the National Security Advisor, jokingly opened his fly in front of a reporter, a claim The Post retracted the following day.
Quinn was critical of President Bill Clinton during the impeachment trial, stating that he had "fouled the nest". Quinn had a long-standing animus for the Clintons, possibly due to a perceived snub by First Lady Hillary Clinton, who declined a party invitation from Quinn. Regarding Whitewater Independent Counsel Ken Starr, she wrote: "Similarly, independent counsel Ken Starr is not seen by many Washington insiders as an out-of-control prudish crusader. Starr is a Washington insider, too. He has lived and worked here for years. He had a reputation as a fair and honest judge. He has many friends in both parties. Their wives are friendly with one another and their children go to the same schools." Harry Jaffe wrote in Salon that Quinn's condemnation of Bill Clinton's adultery rang hollow coming from someone who broke up the marriage of her boss Ben Bradlee before going on to marry Bradlee herself.
On February 19, 2010, The Washington Post published "Sally Quinn's The Party: No 'dueling' Bradlee weddings, just scheduling mistake", in print and online. This was Quinn's last column for the printed newspaper. The column alluded to Bradlee family dysfunction, her son's wedding, which she scheduled on the same day as the wedding of her husband's granddaughter. The column was considered inappropriate and reader backlash was immediate, criticizing Quinn for airing family laundry and Washington Post editors for printing it. By February 24, the Post canceled her column, which had been appearing in the religion section of the print edition.
Television journalism 
In August 1973, Quinn tried her hand at television, joining CBS News reporter Hughes Rudd as co-anchor of the CBS Morning News. The show's anchoring team was its first disaster since debuting in 1963. Quinn was given no training, a huge buildup and ninety minutes before her television debut on August 6, 1973, Quinn, who had never reported for television before, collapsed while trying to fight the flu. Quinn's ad libs during the show's first week tended toward the inappropriate—in one episode, following a report on the children of California migrant farm workers, she quipped that child labor "was how I felt when my mother and father made me clean up my room." Quinn left the CBS Morning News after the February 1, 1974, telecast. She chronicled her short, disastrous television career in the bestselling book We're Going to Make You a Star!
Quinn had a cameo role in Born Yesterday, the 1993 remake of the 1950 romantic comedy.
Andy Warhol did six portraits of Sally Quinn.
- The Party: A Guide To Adventurous Entertaining. New York: Simon & Schuster, 1997.
- We're Going To Make You a Star. New York: Simon & Schuster, 1975.
- "William W. Quinn, 92, General and Former Intelligence Officer". The New York Times. 12 Sep 2000. pp. B10. Retrieved 5 Jan 2010.
- "What My Son Taught Me About God", The Washington Post, December 7, 2006.
- "Television: Sallying Forth". Time. 1973-08-20. Retrieved 2010-05-23.
- "Press: Brzezinski's Zipper Was Up". Time. 1979-12-31. Retrieved 2010-05-23.
- The Washington Post. 1998-11-02 http://www.washingtonpost.com/wp-srv/politics/special/clinton/stories/quinn110298.htm
|url=missing title (help). Retrieved 2010-05-23.
- Salon | Media Circus: The (not so) mighty Quinn
- TWM - The Clinton-Lewinsky Obsession/Gitlin
- Quinn's column was canceled after this article
- "Wedded dis for Bradlee brood" Boston Herald February 18, 2010
- "Sally Quinn Loses Washington Post Column After Wedding Drama" Medialite February 25, 2010
- The Encyclopedia of Daytime Television, by Wesley Hyatt (Billboard Books, 1997)
- Bernstein, Adam (April 13, 2009). "Cherif Guellal dies at 76; Algerian resistance fighter and diplomat". Los Angeles Times. Retrieved April 13, 2009.
- Bass, Jack; Thompson, Marilyn (2006). Strom: The Complicated Personal And Political Life of Strom Thurmond. PublicAffairs Books. p. 225. Retrieved June 14, 2012.
- "Private Tour — Ben Bradlee & Sally Quinn", Home & Design, November?December 2008.
- Sally Quinn at the Internet Movie Database
- Booknotes interview with Quinn on The Party: A Guide to Adventurous Entertaining, December 28, 1997.