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Not to be confused with squalene.
Skeletal formula of squalane
CAS number 111-01-3 YesY
PubChem 8089
ChemSpider 7798 N
UNII GW89575KF9 YesY
EC number 203-825-6
KEGG D05915 N
MeSH squalane
RTECS number XB6070000
Beilstein Reference 776019
Jmol-3D images Image 1
Molecular formula C30H62
Molar mass 422.81 g mol−1
Appearance Colorless liquid
Odor Odorless
Density 810 mg mL−1
Melting point −38 °C (−36 °F; 235 K)
Boiling point 176 °C (349 °F; 449 K) at 7 Pa
Refractive index (nD) 1.452
heat capacity
886.36 J K−1 mol−1
Std enthalpy of
−871.1–−858.3 kJ mol−1
Std enthalpy of
−19.8062–−19.7964 MJ mol−1
GHS pictograms The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word WARNING
GHS hazard statements H315, H319, H335
GHS precautionary statements P261, P305+351+338
EU classification Irritant Xi
R-phrases R36/37/38
S-phrases S26, S36
Flash point 218 °C (424 °F; 491 K)
Related compounds
Related alkanes Phytane
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Squalane is a hydrocarbon and triterpene derived by hydrogenation of squalene.

Due to the complete saturation of squalane, it is not subject to auto-oxidation. This fact, coupled with lower costs associated with squalane make it desirable in cosmetic applications where it is used as an emollient and moisturizer.[2]

The label of squalane as "natural moisturizer" is somewhat exaggerated. While squalane can be found in small quantities in sebaceous secretions (sebum), it is squalene that is most commonly found in nature, most notably in the livers of sharks.[3]

Squalane has low acute toxicity and is not an irritant at the concentrations used in cosmetics.[4]


  1. ^ "squalane - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification and Related Records. Retrieved 15 March 2012. 
  2. ^ "Squalane: the natural moisturizer", by Rosenthal, Maurice L. in Chemistry and Manufacture of Cosmetics (3rd Edition), Editor: Schlossman, Mitchell L. (2002), 3(Bk. 2), 869-875
  3. ^ Allison, Anthony C. (1999). "Squalene and Squalane Emulsions as Adjuvants". Methods 19 (1): 87–93. doi:10.1006/meth.1999.0832. 
  4. ^ "Final report on the safety assessment of squalane and squalene". Journal of the American College of Toxicology 1 (2): 37–56. 1982. doi:10.3109/10915818209013146.