Streptomyces coelicolor
Streptomyces coelicolor | |
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Species: | S. coelicolor
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Streptomyces coelicolor |
Streptomyces coelicolor is a soil-dwelling Gram-positive bacterium that belongs to the genus Streptomyces.[1]
Genome
The genome of one strain of S. coelicolor was sequenced in 2002.[2] It contains 8,667,507 bp, encoding 7,825 predicted genes, including over 20 gene clusters for the synthesis of known or predicted natural products.
Usage in biotechnology
Strains of S. coelicolor produce various antibiotics, including actinorhodin, methylenomycin, undecylprodigiosin,[3] and perimycin.[4][5] Certain strains of S. coelicolor can be used for heterologous protein expression.[1]
References
- ^ a b "Streptomyces coelicolor". John Innes Center. Retrieved 25 January 2010.
- ^ Bentley SD, Chater KF, Cerdeño-Tárraga AM; et al. (May 2002). "Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)". Nature. 417 (6885): 141–7. doi:10.1038/417141a. PMID 12000953.
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(help)CS1 maint: multiple names: authors list (link) - ^ Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. PMC 178074. PMID 8655502.
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: CS1 maint: multiple names: authors list (link) - ^ Liu CM, McDaniel LE, Schaffner CP (March 1972). "Fungimycin, biogenesis of its aromatic moiety". The Journal of Antibiotics. 25 (3): 187–8. doi:10.7164/antibiotics.25.187. PMID 5034814.
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: CS1 maint: multiple names: authors list (link) - ^ Lee CH, Schaffner CP (May 1969). "Perimycin. The structure of some degradation products". Tetrahedron. 25 (10): 2229–32. doi:10.1016/S0040-4020(01)82770-8. PMID 5788396.