TRAK2

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Trafficking protein, kinesin binding 2
Identifiers
Symbols TRAK2 ; ALS2CR3; CALS-C; GRIF-1; GRIF1; MILT2; OIP98
External IDs OMIM607334 MGI1918077 HomoloGene22861 GeneCards: TRAK2 Gene
RNA expression pattern
PBB GE TRAK2 202125 s at tn.png
PBB GE TRAK2 202124 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 66008 70827
Ensembl ENSG00000115993 ENSMUSG00000026028
UniProt O60296 Q6P9N8
RefSeq (mRNA) NM_015049 NM_172406
RefSeq (protein) NP_055864 NP_765994
Location (UCSC) Chr 2:
202.24 – 202.32 Mb
Chr 1:
58.9 – 58.97 Mb
PubMed search [1] [2]

Trafficking kinesin-binding protein 2 is a protein that in humans is encoded by the TRAK2 gene.[1][2][3]


Interactions[edit]

TRAK2 has been shown to interact with Kir2.1[4] and GABRB2.[5]

References[edit]

  1. ^ Hadano S, Yanagisawa Y, Skaug J, Fichter K, Nasir J, Martindale D, Koop BF, Scherer SW, Nicholson DW, Rouleau GA, Ikeda J, Hayden MR (Feb 2001). "Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2". Genomics 71 (2): 200–13. doi:10.1006/geno.2000.6392. PMID 11161814. 
  2. ^ Gilbert SL, Zhang L, Forster ML, Anderson JR, Iwase T, Soliven B, Donahue LR, Sweet HO, Bronson RT, Davisson MT, Wollmann RL, Lahn BT (Jan 2006). "Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice". Nat Genet 38 (2): 245–50. doi:10.1038/ng1715. PMID 16380713. 
  3. ^ "Entrez Gene: TRAK2 trafficking protein, kinesin binding 2". 
  4. ^ Grishin, Anatoly; Li Hui, Levitan Edwin S, Zaks-Makhina Elena (Oct 2006). "Identification of gamma-aminobutyric acid receptor-interacting factor 1 (TRAK2) as a trafficking factor for the K+ channel Kir2.1". J. Biol. Chem. (United States) 281 (40): 30104–11. doi:10.1074/jbc.M602439200. ISSN 0021-9258. PMID 16895905. 
  5. ^ Beck, Mike; Brickley Kieran; Wilkinson Helen L; Sharma Seema; Smith Miriam; Chazot Paul L; Pollard Simon; Stephenson F Anne (Aug 2002). "Identification, molecular cloning, and characterization of a novel GABAA receptor-associated protein, GRIF-1". J. Biol. Chem. (United States) 277 (33): 30079–90. doi:10.1074/jbc.M200438200. ISSN 0021-9258. PMID 12034717. 

Further reading[edit]