Talk:Macrophage colony-stimulating factor

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Low-importance).

Medicine Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.

Cytokine or chemokine?[edit]

According to my book ("Medizinische Mikrobiologie und Immunologie"; Hahn, Falke, Kaufmann, Ullmann; Springer-Verlag, Heidelberg, 5. Aufl., 2004; ISBN 3-540-21971-4) M-CSF is a chemokine, not a cytokine. Could someone more knowledgeable than me clarify on this one? 85.180.189.77 (talk) 06:59, 20 March 2012 (UTC)[reply]

I appologies in advance if I'm writting in the wrong place in an attempt to answer this. I'm new to commenting on wikipedia (but long term user) and unfamiliar with coding.

However, I'll try to answer your question, despite that almost two years have passed.

A good review of cytokines and chemokines can be found here: http://www.ncbi.nlm.nih.gov/pubmed/12592293 Just to summarise:

Cytokines are a broad cathegory of small secreted proteins that can cause proliferation, differentiation activation or inactivation of cells within the immune system. Chemokines are a subgroup of cytokines, that are involved in motility of immune cells. Thus, they are involved in chemotaxis and subsequent adhesion of the immune cells. Using this classification, I would argue that CSF-1 / M-CSF is a cytokine and cannot be classified as a chemokine(and so does the NCBI description http://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=1435. Why your book says otherwise, I do not know. I do not know it, but it does sound decent. I hope this helped?212.88.77.66 (talk) 10:38, 19 February 2014 (UTC)[reply]