The common initial dose should be .05cc to .2cc depending on the patients level of ED. Wait 48 hours before increasing dosage. Increase by 0.025 cc to 0.050 cc until a satisfactory dose is reached, or sometime it may subject to change by the doctor and or pharmacy. Its a strict prescribed medicine, due to the varying amount of dose, Purchasing/selling with out prescription is illegal.
^R Seyam, K Mohamed, A Al Akhras and H Rashwan (2005). "A prospective randomized study to optimize the dosage of trimix ingredients and compare its efficacy and safety with prostaglandin E1". International Journal of Impotence Research: the Journal of Sexual Medicine17 (4): 346–353. doi:10.1038/sj.ijir.3901313. PMID15772683.
^S.C. Kim, I.H. Chang, H.J. Jeon (August 2003). "Preference for oral sildenafil or intracavernosal injection in patients with erectile dysfunction already using intracavernosal injection for > 1 year". BJU International92 (3): 277–280. doi:10.1046/j.1464-410X.2003.04324.x. PMID12887483.
^S. Israilov; Baniel, J; Shmueli, J; Niv, E; Engelstein, D; Segenreich, E; Livne, PM (2004). "Treatment program for erectile dysfunction in patients with cardiovascular diseases". The American Journal of Cardiology93 (6): 689–693. doi:10.1016/j.amjcard.2003.11.049. PMID15019870.