User:Hadoooookin/to do list/pharmaceutical
DRUG DESIGN (Parker) The molecular mechanisms by which drugs act in the body. What is drug formulation? Process of:
- devising
- preparing
- developing
- manufacturing
- producing the end product
Type of product:
- capsule
- tablet
- cream
Drug profile:
- Origin
- Chemistry
- Action / pharmacology
- Uses
- Preparation
Module Descriptor: brief description of module Integrated module: issues
- Drug discovery
- Drug design
- Drug development
- Drug action: chemical aspects
- The consequences of product formulation on the effectiveness of drugs
Module descriptors: Aims
- Chemical basis of drug-receptor interactions
- Approaches to rational drug design and development
- relate chemical structure and associated physicochemical properties to stability, ADME
- relate drug molecule chemistry to the formulation, uniformity, bioavailability, and stability of pharmaceutical products
- preformulation requirements of new drug entities
- formulation requirements
- quality assurance
- GMP
- natural products
Module descriptor: learning outcomes
- Drug target interactions principles
- Bonding
- Complementarity
- Optical and geometric specificity of isomers
- Rational drug design and development
- Structural aspects of
- Drug-enzyme interactions
- Drug-receptor interactions
- Drug development by structural modification
- Biopharmaceutics wrt the physciochemical parameters of drugs
- Drug metabolism and transfer
- Metabolic processes that occur at sites on drug molecules
- Possible metabolites produced
- Effect of processes on drug activity