In 1463, King Boromma Trailokanat (1448-1488) of Ayutthaya moved the capital of his empire to Phitsanulok, and ordered the establishment of new temples, as well as the restoration of existing older ones. Wat Ratchaburana dates back to the beginning of his reign in Phitsanulok. He ordered the construction a chedi and other buildings on the temple's campus. Today, the impressive chedi is nearly all that remains of the original construction. However, other buildings have been constructed among the ruins. At one time, King Mongkut (Rama IV) headed a construction and restoration project of the temple.
The most significant feature is the nearly 600 year old chedi, dating back to the time of King Trailokanat. The chedi is said to enshrine relics of the Buddha. However, there is no access to the chedi's spire. Wat Ratchaburana has an unusual roof structure. Also, in the nearby shrine, a very nice Sukhothai style Buddha figure is situated amidst red painted columns. In addition, the shrine houses a showroom displaying old coins, bank notes, musical instruments and glass objects. The walls are decorated with artistic frescoes. An old bell tower, Hor Rakhang, as well as a recently construcetd shrine with a garden and six swan figures stand beside the monastery. There is also a meeting hall on the camups.