Zineb

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Zineb
Zn2+.svg Zineb.svg
Identifiers
CAS number 12122-67-7 YesY
PubChem 3032296
ChemSpider 2297309 N
EC number 235-180-1
KEGG C15232 YesY
RTECS number ZH3325000
Jmol-3D images Image 1
Properties
Molecular formula C4H6N2S4Zn
Molar mass 275.77 g mol−1
Appearance pale yellow powder
Hazards
EU Index 006-078-00-2
EU classification Irritants (Xi)
Sensitizers
R-phrases R37 R43
S-phrases (S2) S8 S24/25 S46
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Zineb is an organosulfur compound, formally the zinc salt of a bis-dithiocarbamate, which is used as fungicide. It is a pale yellow solid.

Synthesis and applications[edit]

Zineb and is a polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand.[1] Its uses include control of downy mildews, rusts and redfire disease.[1] It is produced by reacting ethylene bis(dithiocarbamate) sodium salt, "nabam", with zinc sulfate. This procedure can be carried out by mixing nabam and zinc sulfate in the spray tank.[2]

Its uses include control of downy mildews, rusts and redfire disease.[1] In the US it was once registered as a "General Use Pesticide", however all registrations were voluntarily cancelled following an EPA special review.[2] It continues to be used in many other countries. Zineb has been described to interfere with glucocorticoid metabolism, by inhibiting the activity of the enzyme 11beta-hydroxysteroiddehydrogenase type 2, which converts cortisol to cortisone.[3]

See also[edit]

References[edit]

  1. ^ a b c Ullmann's Agrochemicals, Wiley-VCH Staff , Wiley-Vch (COR), 2007 ISBN 3-527-31604-3
  2. ^ a b Michael A. Kamrin, (1997) Pesticide Profiles: Toxicity, Environmental Impact, and Fate, CRC Press, ISBN 1-56670-190-2
  3. ^ Atanasov AG, Tam S, Röcken JM, Baker ME,Odermatt A. Inhibition of 11beta-hydroxysteroid dehydrogenase type 2 bydithiocarbamates. Biochem Biophys ResCommun. 2003 Aug 22;308(2):257-62. PubMedPMID: 12901862. http://www.ncbi.nlm.nih.gov/pubmed/12901862

External links[edit]