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{{Orphan|date=July 2022}}
{{Orphan|date=July 2022}}
{{Infobox scientist
{{Infobox scientist
| name = María S. (Marisol) Soengas
| name = Marisol S. Soengas
| birth_date = {{Birth year and age|1968}}
| birth_date = {{Birth year and age|1968}}
| birth_place = [[Agolada]]
| birth_place = [[Agolada]]
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}}
}}


'''María S. (Marisol) Soengas''' (born 1968) is a Spanish immunologist and Professor at the [[Spanish National Cancer Research Centre|Spanish National Cancer Research Center]] (CNIO). Her research considers melanoma and the development of new therapeutic strategies. She was elected to the [[European Molecular Biology Organization]] in 2022.
'''Marisol S. Soengas''' (born 1968) is a Spanish immunologist who is a professor at the [[Spanish National Cancer Research Centre|Spanish National Cancer Research Center]] (CNIO). Her research considers melanoma and the development of new therapeutic strategies. She was elected to the [[European Molecular Biology Organization]] in 2022.


== Early life and education ==
== Early life and education ==
Soengas was born in [[Agolada]].<ref>{{Cite web |last=www.axel-k.com |title=María S. Soengas |url=https://www.cnio.es/en/personas/maria-s-soengas-2/ |access-date=2022-07-09 |website=CNIO |language=en-US}}</ref> She was an undergraduate student at the [[University of A Coruña]], and moved to the [[Autonomous University of Madrid]] for her doctoral research. She worked in [[molecular biology]] with M. Salas in the Centro de Biología Molecular Severo Ochoa. After earning her doctorate she worked as a postdoctoral scholar at the [[Cold Spring Harbor Laboratory]] and at the [[University of Michigan]].<ref name=":0">{{Cite web |date=2015-03-24 |title=Conference: ""Three-in-One" antimelanoma agents validated in vivo: differential targeting of tumor cells, the surrounding vasculature and the immune system"-Dra. Marisol Soengas, Head Melanoma Group, Dean for Academic Affairs, CNIO |url=https://www.usc.es/cimus/es/events/conference-three-one-antimelanoma-agents-validated-vivo-differential-targeting-tumor-cells |access-date=2022-07-09 |website=CiMUS - USC - Universidad de Santiago de Compostela |language=es}}</ref> At the [[Cold Spring Harbor Laboratory]] she characterised the paoptotic factors as [[melanoma]] suppressors.<ref name=":1">{{Cite web |title=The Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award {{!}} The European Association for Cancer Research |url=https://www.eacr.org/pezcoller-foundation-awards/women-in-cancer-research-award |access-date=2022-07-09 |website=www.eacr.org}}</ref> After deciding to expand beyond cellular/animal models, Soengas moved to the dermatology department in Michigan, home to the Multidisciplinary Melanoma Clinics.<ref name=":1" />
Soengas was born in [[Agolada]].<ref>{{Cite web |last=www.axel-k.com |title=María S. Soengas |url=https://www.cnio.es/en/personas/maria-s-soengas-2/ |access-date=2022-07-09 |website=CNIO |language=en-US}}</ref> She was an undergraduate student at the [[University of A Coruña]], and moved to the [[Autonomous University of Madrid]] for doctoral research. She worked in [[molecular biology]] with M. Salas in the Centro de Biología Molecular Severo Ochoa. She worked as a postdoctoral scholar at the [[Cold Spring Harbor Laboratory]] and at the [[University of Michigan]].<ref name=":0">{{Cite web |date=2015-03-24 |title=Conference: ""Three-in-One" antimelanoma agents validated in vivo: differential targeting of tumor cells, the surrounding vasculature and the immune system"-Dra. Marisol Soengas, Head Melanoma Group, Dean for Academic Affairs, CNIO |url=https://www.usc.es/cimus/es/events/conference-three-one-antimelanoma-agents-validated-vivo-differential-targeting-tumor-cells |access-date=2022-07-09 |website=CiMUS - USC - Universidad de Santiago de Compostela |language=es}}</ref> At the Cold Spring Harbor Laboratory, she characterised the apoptotic factors as [[melanoma]] suppressors.<ref name=":1">{{Cite web |title=The Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award {{!}} The European Association for Cancer Research |url=https://www.eacr.org/pezcoller-foundation-awards/women-in-cancer-research-award |access-date=2022-07-09 |website=www.eacr.org}}</ref> After deciding to expand beyond cellular/animal models, Soengas moved to the dermatology department in Michigan, home to the Multidisciplinary Melanoma Clinics.<ref name=":1" />


== Research and career ==
== Research and career ==
In 2008 Soengas joined the [[Spanish National Cancer Research Centre|Spanish National Cancer Research Center]] (CNIO), where she established a research programme that looked to understand [[melanoma]], and to translate cutting-edge scientific research into clinical practise.<ref name=":0" /><ref>{{Cite web |last=www.axel-k.com |title=Melanoma Group |url=https://www.cnio.es/en/research-innovation/scientific-programmes/molecular-oncology-programme/melanoma-group/ |access-date=2022-07-09 |website=CNIO |language=en-US}}</ref> Melnomas are an aggressive form of cancer, and whilst various strategies have been proposed to improve patients' prognoses, new therapeutic agents are desperately needed. Sonegas looks to identify new biomarkers of disease, and the mechanisms of cellular stress that are deregulated in melanoma.
In 2008, Soengas joined the [[Spanish National Cancer Research Centre|Spanish National Cancer Research Center]] (CNIO), where she established a research program that looked to understand [[melanoma]], and to translate cutting-edge scientific research into clinical practice.<ref name=":0" /><ref>{{Cite web |last=www.axel-k.com |title=Melanoma Group |url=https://www.cnio.es/en/research-innovation/scientific-programmes/molecular-oncology-programme/melanoma-group/ |access-date=2022-07-09 |website=CNIO |language=en-US}}</ref> Sonegas looks to identify new biomarkers of disease, and the mechanisms of cellular stress that are deregulated in melanoma. Her group were the first to describe a lymphoreporter (MetAlert) mice for non-invasive imaging of pre-metastatic niches in melanoma. This allowed her to understand the mechanisms of immune resistance as well as to generate nanoparticle-based treatments.{{cn}}

Her group were the first to describe a lymphoreporter (MetAlert) mice for non-invasive imaging of pre-metastatic niches in melanoma. This allowed her to undestand the mechanisms of immune resistance as well as to generate nanoparticle-based treatments.

== Awards and honours ==


== Awards and honors ==
* Dana Ashby Young Investigator Award of the Society for Melanoma Research<ref name=":1" />
* Dana Ashby Young Investigator Award of the Society for Melanoma Research<ref name=":1" />
* 2009 Premio M. Josefa Wonenburger from the Xunta de Galicia<ref>{{Cite web |title=Premio María Josefa Wonenburger {{!}} Unidade Muller e Ciencia |url=https://unidadedamullereciencia.xunta.gal/es/premio-maria-josefa-wonenburger |access-date=2022-07-09 |website=unidadedamullereciencia.xunta.gal}}</ref>
* 2009 Premio M. Josefa Wonenburger from the Xunta de Galicia<ref>{{Cite web |title=Premio María Josefa Wonenburger {{!}} Unidade Muller e Ciencia |url=https://unidadedamullereciencia.xunta.gal/es/premio-maria-josefa-wonenburger |access-date=2022-07-09 |website=unidadedamullereciencia.xunta.gal}}</ref>
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* 2022 Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award<ref name=":1" />
* 2022 Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award<ref name=":1" />


== Select publications ==
== Selected publications ==

* {{Cite Q|Q31984891}}
* {{Cite Q|Q31984891}}
* {{Cite Q|Q29619550}}
* {{Cite Q|Q29619550}}
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{{Authority control}}
{{Authority control}}
{{DEFAULTSORT:Soengas, Maria}}[[Category:Living people]]

{{DEFAULTSORT:Soengas, Maria}}
[[Category:Living people]]
[[Category:1968 births]]
[[Category:1968 births]]
[[Category:Autonomous University of Madrid alumni]]
[[Category:Autonomous University of Madrid alumni]]

Revision as of 13:08, 15 July 2022

Marisol S. Soengas
Born1968 (age 55–56)
Alma materAutonomous University of Madrid
University of A Coruña
Scientific career
InstitutionsUniversity of Michigan
Cold Spring Harbor Laboratory
Spanish National Cancer Research Centre

Marisol S. Soengas (born 1968) is a Spanish immunologist who is a professor at the Spanish National Cancer Research Center (CNIO). Her research considers melanoma and the development of new therapeutic strategies. She was elected to the European Molecular Biology Organization in 2022.

Early life and education

Soengas was born in Agolada.[1] She was an undergraduate student at the University of A Coruña, and moved to the Autonomous University of Madrid for doctoral research. She worked in molecular biology with M. Salas in the Centro de Biología Molecular Severo Ochoa. She worked as a postdoctoral scholar at the Cold Spring Harbor Laboratory and at the University of Michigan.[2] At the Cold Spring Harbor Laboratory, she characterised the apoptotic factors as melanoma suppressors.[3] After deciding to expand beyond cellular/animal models, Soengas moved to the dermatology department in Michigan, home to the Multidisciplinary Melanoma Clinics.[3]

Research and career

In 2008, Soengas joined the Spanish National Cancer Research Center (CNIO), where she established a research program that looked to understand melanoma, and to translate cutting-edge scientific research into clinical practice.[2][4] Sonegas looks to identify new biomarkers of disease, and the mechanisms of cellular stress that are deregulated in melanoma. Her group were the first to describe a lymphoreporter (MetAlert) mice for non-invasive imaging of pre-metastatic niches in melanoma. This allowed her to understand the mechanisms of immune resistance as well as to generate nanoparticle-based treatments.[citation needed]

Awards and honors

  • Dana Ashby Young Investigator Award of the Society for Melanoma Research[3]
  • 2009 Premio M. Josefa Wonenburger from the Xunta de Galicia[5]
  • 2013 Melanoma Research Alliance Award[6]
  • 2016 L’Oreal-MRA Women-Lead Team Award[7]
  • 2022 Elected to the European Molecular Biology Organization[8]
  • 2022 Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award[3]

Selected publications

  • Soengas MS; Capodieci P; Polsky D; et al. (1 January 2001). "Inactivation of the apoptosis effector Apaf-1 in malignant melanoma". Nature. 409 (6817): 207–211. doi:10.1038/35051606. ISSN 1476-4687. PMID 11196646. Wikidata Q31984891.
  • Chrysiis Michaloglou; Liesbeth C W Vredeveld; Marisol Soengas; et al. (1 August 2005). "BRAFE600-associated senescence-like cell cycle arrest of human naevi". Nature. 436 (7051): 720–724. doi:10.1038/NATURE03890. ISSN 1476-4687. PMID 16079850. Wikidata Q29619550.
  • María S Soengas; Scott W Lowe (1 May 2003). "Apoptosis and melanoma chemoresistance". Oncogene. 22 (20): 3138–3151. doi:10.1038/SJ.ONC.1206454. ISSN 0950-9232. PMID 12789290. Wikidata Q35146577.
  • Marisol Soengas; Alarcón RM; Yoshida H; Giaccia AJ; Hakem R; Mak TW; Lowe SW (1 April 1999). "Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition". Science. 284 (5411): 156–159. doi:10.1126/SCIENCE.284.5411.156. ISSN 0036-8075. PMID 10102818. Wikidata Q53425055.

References