Streptolydigin: Difference between revisions

Streptolydigin
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-[4-[6-(1,6-dimethylspiro[8,9-dioxabicyclo[3.3.1]non-3-ene-2,2'-oxirane]-7;
CAS Number	7229-50-7 ;
PubChem CID	220508;
DrugBank	DB04785 ;
ChemSpider	16736035 ;
ChEMBL	ChEMBL1236068 ;
CompTox Dashboard (EPA)	DTXSID20905083 ;
Chemical and physical data
Formula	C32H44N2O9
Molar mass	600.708 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CNC(=O)C(C)C2C(=O)/C(C(=O)N2C1CCC(O)C(C)O1)=C(\O)/C=C/C(/C)=C/C(C)C5OC4(C)OC(\C=C/C34CO3)C5C;
	InChI InChI=1S/C32H44N2O9/c1-16(14-17(2)28-18(3)23-12-13-32(15-40-32)31(6,42-23)43-28)8-9-22(36)25-27(37)26(19(4)29(38)33-7)34(30(25)39)24-11-10-21(35)20(5)41-24/h8-9,12-14,17-21,23-24,26,28,35-36H,10-11,15H2,1-7H3,(H,33,38)/b9-8+,16-14+,25-22+ ; Key:KVTPRMVXYZKLIG-NCFIBNQNSA-N ;
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Revision as of 11:37, 23 January 2012

Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.

This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.

@@ Line 30: / Line 30: @@
 | ChemSpiderID = 16736035
 | ChEMBL_Ref = {{ebicite|changed|EBI}}
-| ChEMBL = 1628265
+| ChEMBL = 1236068
 <!--Chemical data-->