Wikipedia talk:WikiProject Pharmacology

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WikiProject Pharmacology (Rated NA-class)
WikiProject iconThis page is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.
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Carbon Monoxide[edit]

The carbon monoxide-releasing molecules page has recently been expanded. This focuses on CORMs, CO, heme oxygenase as part of the therapeutic gases niche. Feedback is welcome. — Preceding unsigned comment added by Ketoacids (talkcontribs) 14:07, 23 August 2018 (UTC)

Rating (pharmaceutical industry)[edit]

The stub at Rating (pharmaceutical industry) appears to actually treat rater training – that is, training designed to lead to higher inter-rater reliability. I'm not sure whether the page should be moved, merged to another article, deleted entirely, or simply cleaned up. Any help from members of this Wikiproject would be appreciated.

(It seems that the page moved twice in the past, from Rater training to Rater, and then to Rating (pharmaceutical industry). Both of the earlier titles currently redirect to this one.) Cnilep (talk) 07:55, 1 September 2018 (UTC)

I agree that the page is problematic. My gut reaction is that there must be a page on a related topic into which it should be merged, but I'm uncertain what that target might be. Perhaps clinical trial or clinical research. --Tryptofish (talk) 19:49, 1 September 2018 (UTC)
I expanded the article and added sources. I think there are enough independent secondary sources to justify an independent article. However I think the article should be moved to Rating (medical treatment) or something similar. Boghog (talk) 09:46, 2 September 2018 (UTC)
Thanks for doing that. My suggestion would be a rename to Rating (clinical trials). It's not really about medical treatment, in the sense of rating what a physician did for a patient, and it's clearly not limited to pharmaceutical therapeutics. --Tryptofish (talk) 20:31, 2 September 2018 (UTC)

Cosmos magazine: diclofenac associated with 50% hike in heart risk compared to non-users.[edit]

So, that's a popular biology comment on:
Schmidt, Morten; Sørensen, Henrik Toft; Pedersen, Lars (4 September 2018). "Diclofenac use and cardiovascular risks: series of nationwide cohort studies". BMJ. 362: k3426. doi:10.1136/bmj.k3426. ISSN 0959-8138.
Reading the paper, it doesn't identify a new problem, and it's incredibly frustrating that the authors report this relative risk, but never bother to calculate the absolute risk nor the 'number needed to harm', either of which would have been very helpful for interpreting the data. Using the relative risk does help grab the headlines, but doesn't help decision-making. You can get a sense of how misleading this is by looking at the 'Event rate' section of that paper, where we read:

Within 30 days, major adverse cardiovascular events occurred among 1465 (0.10%) diclofenac initiators, 2912 (0.07%) ibuprofen initiators, ...

So, 0.07% to 0.10% is about a 40% relative risk increase, but only a 0.03% absolute risk. Klbrain (talk) 15:37, 10 September 2018 (UTC)

Prototype drug[edit]

Just to let you know that I created a stub prototype drug and linked it from several appropriate articles, as I felt that we don't have even a definition of this pretty basic topic. I confess knowing very little about pharmacology so I'm leaving it to the wikiproject to decide whether a standalone article is warranted or it should be merged into drug class. However, I feel that it could potentially grow into a list of prototype drugs, should anyone venture to compile one. (Although not a RS, it's a common enough thing in medical classes such as [1]). No such user (talk) 14:55, 16 October 2018 (UTC)

Cefiderocol[edit]

A new experimental drug, Cefiderocol, has hit the mainstream news. I've created a stub for it, complete with drugbox template, but I can't work out to make it auto-fill from the data already there in Wikidata. -- The Anome (talk) 17:06, 26 October 2018 (UTC)

Featured quality source review RFC[edit]

Editors in this WikiProject may be interested in the featured quality source review RFC that has been ongoing. It would change the featured article candidate process (FAC) so that source reviews would need to occur prior to any other reviews for FAC. Your comments are appreciated. --IznoRepeat (talk) 21:51, 11 November 2018 (UTC)

Input requested[edit]

[2] Enigmamsg 00:18, 12 November 2018 (UTC)

I notified WT:MED. --Tryptofish (talk) 21:55, 12 November 2018 (UTC)