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'''Sphere Fluidics''' is a [[Cambridge, UK]]-based [[Life Sciences]] [[R&D]] company that specializes in [[biopharmaceutical]] discovery and development, [[cell therapy]] engineering, [[bioproduction]] and [[synthetic biology]], [[chemical analysis|analysis]] and isolation. The company is reported to own 25 [[patent]]ed products that include instruments, [[biochip]]s, and specialist [[chemical]]s.<ref name=":0">{{Cite web|url=https://www.businessweekly.co.uk/news/biomedtech/triple-success-cambridge-life-science-pioneers|title=Triple success for Cambridge life science pioneers {{!}} Business Weekly {{!}} Technology News {{!}} Business news {{!}} Cambridge and the East of England|website=www.businessweekly.co.uk|language=en|access-date=2017-12-11}}</ref><ref name=":1">{{Cite news|url=https://www.enterprise.cam.ac.uk/news/sphere-fluidics-wins-7-million-for-development-of-single-cell-analysis-system/|title=Sphere Fluidics wins $7 million for development of single cell analysis system - Cambridge Enterprise|last=|first=|work=Cambridge Enterprise|access-date=2017-12-11|language=en-GB}}</ref>
'''Sphere Fluidics''' is a [[Cambridge, UK|Cambridge(UK]])-based [[Life Sciences]] [[R&D]] company that specializes in [[biopharmaceutical]] discovery and development, [[cell therapy]] engineering, [[bioproduction]] and [[synthetic biology]], [[chemical analysis|analysis]] and isolation. The company is reported to own 25 [[patent]]ed products that include instruments, [[biochip]]s, and specialist [[chemical]]s.<ref name=":0">{{Cite web|url=https://www.businessweekly.co.uk/news/biomedtech/triple-success-cambridge-life-science-pioneers|title=Triple success for Cambridge life science pioneers {{!}} Business Weekly {{!}} Technology News {{!}} Business news {{!}} Cambridge and the East of England|website=www.businessweekly.co.uk|language=en|access-date=2017-12-11}}</ref><ref name=":1">{{Cite news|url=https://www.enterprise.cam.ac.uk/news/sphere-fluidics-wins-7-million-for-development-of-single-cell-analysis-system/|title=Sphere Fluidics wins $7 million for development of single cell analysis system - Cambridge Enterprise|last=|first=|work=Cambridge Enterprise|access-date=2017-12-11|language=en-GB}}</ref>


== Overview ==
== Overview ==
Sphere Fluidics was originally established in 2010, with two chemistry [[professor]]s of [[Cambridge University]], namely, Professor [[Chris Abell]] and Professor [[:nl:Wilhelm Huck|Wilhelm Huck]], Dr. Frank F. Craig, an entrepreneur, and Dr. Maher Khaled, a Cambridge University Enterprise, as founders.<ref name=":0" /><ref name=":2">{{Cite web|url=https://www.gov.uk/government/news/sphere-fluidics-biotherapeutics-device-attracts-7m-investment|title=Sphere Fluidics: biotherapeutics device attracts $7m investment - GOV.UK|website=www.gov.uk|language=en|access-date=2017-12-11}}</ref><ref name=":3" />
Sphere Fluidics was originally established in 2010, by two chemistry [[professor]]s of [[Cambridge University]], namely, Professor [[Chris Abell]] and Professor [[:nl:Wilhelm Huck|Wilhelm Huck]], Dr. Frank F. Craig, an entrepreneur, and Dr. Maher Khaled, a Cambridge University Enterprise executive, as founders.<ref name=":0" /><ref name=":2">{{Cite web|url=https://www.gov.uk/government/news/sphere-fluidics-biotherapeutics-device-attracts-7m-investment|title=Sphere Fluidics: biotherapeutics device attracts $7m investment - GOV.UK|website=www.gov.uk|language=en|access-date=2017-12-11}}</ref><ref name=":3" />


== Funding ==
== Funding ==
November 2021: Sphere Fluidics raised $40M led by [[Paris]]-based [[Sofinnova|Sofinnova Partners]] and [[San Francisco]]-based Redmile Group.<ref name=":4">{{Cite web|last=biopharma-reporter.com|title=Sphere Fluidics closes $40m funding round|url=https://www.biopharma-reporter.com/Article/2021/11/05/Sphere-Fluidics-closes-40m-funding-round|access-date=2021-11-29|website=biopharma-reporter.com|language=en-GB}}</ref>
The total funds raised by Sphere Fluidics as of 2017, is reported to be, $13 million through various funding rounds and grants.<ref name=":2" /><ref name=":1" /><ref name=":3" />

The total funds raised by Sphere Fluidics as of 2021, is reported to be, $53 million through various funding rounds, loans and grants.<ref name=":4" /><ref name=":2" /><ref name=":1" /><ref name=":3" />


== Cyto-Mine Technology ==
== Cyto-Mine Technology ==
Cyto-Mine is a patented single [[Cell (biology)|cell]] analysis and characterisation system by Sphere Fluidics. This technology is said to aid the development of biotherapeutics for treatment of [[cancer]] and [[inflammatory diseases]] and [[vaccine]] generation. Cyto-Mine is said to be an integrated device which can automatically perform single cell analysis, sorting, imaging and dispensing into individual wells of [[Microplate|microtiter plates]] in a single compact system.<ref>{{Cite news|url=https://www.genomeweb.com/business-news/sphere-fluidics-geneva-biotech-receive-16m-grant-develop-dna-cargo-delivery-system|title=Sphere Fluidics, Geneva Biotech Receive €1.6M Grant to Develop DNA Cargo Delivery System|work=GenomeWeb|access-date=2017-12-11|language=en}}</ref><ref>{{Cite web|url=https://www.the-scientist.com/?articles.view/articleNo/50682/title/TTP-Plc-and-Sphere-Fluidics-introduce-Cyto-Mine-Single-Cell-Analysis-System/|title=TTP Plc and Sphere Fluidics introduce Cyto-Mine Single Cell Analysis System|website=The Scientist|access-date=2017-12-11}}</ref><ref name=":2" />
Cyto-Mine is a patented single [[Cell (biology)|cell]] analysis and characterisation system by Sphere Fluidics. This technology is said to aid the development of [[Biopharmaceutical|biotherapeutics]] for treatment of [[cancer]] and [[inflammatory diseases]] and [[vaccine]] generation. Cyto-Mine is said to be an integrated device which can automatically perform single cell analysis, sorting, imaging and dispensing into individual wells of [[Microplate|microtiter plates]] in a single compact system.<ref>{{Cite news|url=https://www.genomeweb.com/business-news/sphere-fluidics-geneva-biotech-receive-16m-grant-develop-dna-cargo-delivery-system|title=Sphere Fluidics, Geneva Biotech Receive €1.6M Grant to Develop DNA Cargo Delivery System|work=GenomeWeb|access-date=2017-12-11|language=en}}</ref><ref>{{Cite web|url=https://www.the-scientist.com/?articles.view/articleNo/50682/title/TTP-Plc-and-Sphere-Fluidics-introduce-Cyto-Mine-Single-Cell-Analysis-System/|title=TTP Plc and Sphere Fluidics introduce Cyto-Mine Single Cell Analysis System|website=The Scientist|access-date=2017-12-11}}</ref><ref name=":2" />

== Developments and Partnerships ==
In 2019, Sphere Fluidics in partnership with Peak Analysis and Automation (PAA) introduced Integrated [[Microplate]] Handling and Single Cell Analysis Capabilities. The addition of S-LAB to the Cyto-Mine provides researchers with a further streamlined solution for single cell analysis in biopharmaceutical workflows.<ref>{{Cite web|title=Sphere Fluidics and PAA Introduce Integrated Microplate Handling and Single Cell Analysis Capabilities|url=https://www.labmanager.com/product-news/sphere-fluidics-and-paa-introduce-integrated-microplate-handling-and-single-cell-analysis-capabilities-577|access-date=2021-11-29|website=Lab Manager|language=en}}</ref>

On 10 November 2021, Sphere Fluidics in partnership with ClexB gave away 10 [[Cyrix|CYTRIX]] [[Microfluidics|microfluidic]] [[hydrogel]] kits containing the novel CYTRIX hydrogel, Pico-Surf™ surfactant and Sphere Fluidics’ Pico-Gen™ double aqueous biochip, giving a plug-and-play system for microfluidic single-cell hydrogel [[Encapsulation (computer programming)|encapsulation]], marking the celebration of [[World Science Day for Peace and Development|World Science Day for Peace and Development.]]<ref>{{Cite web|date=2021-11-12|title=Sphere Fluidics and ClexBio giving away CYTRIX hydrogel kits|url=https://www.news-medical.net/news/20211112/Sphere-Fluidics-and-ClexBio-Giving-Away-CYTRIX-Hydrogel-Kits.aspx|access-date=2021-11-29|website=News-Medical.net|language=en}}</ref>


== Awards ==
== Awards ==
Line 28: Line 35:


2017: European Product Innovation Award<ref name=":0" /><ref>{{Cite news|url=https://ww2.frost.com/news/press-releases/frost-sullivan-commends-sphere-fluidics-its-innovative-single-cell-analysis-platform-solution/|title=Frost & Sullivan Commends Sphere Fluidics for Its Innovative Single-cell Analysis Platform Solution}}</ref>
2017: European Product Innovation Award<ref name=":0" /><ref>{{Cite news|url=https://ww2.frost.com/news/press-releases/frost-sullivan-commends-sphere-fluidics-its-innovative-single-cell-analysis-platform-solution/|title=Frost & Sullivan Commends Sphere Fluidics for Its Innovative Single-cell Analysis Platform Solution}}</ref>

2020: [[Queen's Awards for Enterprise|Queen’s Award for Enterprise for Innovation]]<ref>{{Cite web|date=2020-04-21|title=Sphere Fluidics receives Queen’s Award for Enterprise|url=https://www.news-medical.net/news/20200421/Sphere-Fluidics-receives-Queene28099s-Award-for-Enterprise.aspx|access-date=2021-11-29|website=News-Medical.net|language=en}}</ref>


== References ==
== References ==

Revision as of 02:53, 29 November 2021

Sphere Fluidics
Company typePrivate
Founded2010; 14 years ago (2010)[1]
HeadquartersCambridge, UK
ServicesResearch and Development
Websitespherefluidics.com

Sphere Fluidics is a Cambridge(UK)-based Life Sciences R&D company that specializes in biopharmaceutical discovery and development, cell therapy engineering, bioproduction and synthetic biology, analysis and isolation. The company is reported to own 25 patented products that include instruments, biochips, and specialist chemicals.[2][3]

Overview

Sphere Fluidics was originally established in 2010, by two chemistry professors of Cambridge University, namely, Professor Chris Abell and Professor Wilhelm Huck, Dr. Frank F. Craig, an entrepreneur, and Dr. Maher Khaled, a Cambridge University Enterprise executive, as founders.[2][4][5]

Funding

November 2021: Sphere Fluidics raised $40M led by Paris-based Sofinnova Partners and San Francisco-based Redmile Group.[6]

The total funds raised by Sphere Fluidics as of 2021, is reported to be, $53 million through various funding rounds, loans and grants.[6][4][3][5]

Cyto-Mine Technology

Cyto-Mine is a patented single cell analysis and characterisation system by Sphere Fluidics. This technology is said to aid the development of biotherapeutics for treatment of cancer and inflammatory diseases and vaccine generation. Cyto-Mine is said to be an integrated device which can automatically perform single cell analysis, sorting, imaging and dispensing into individual wells of microtiter plates in a single compact system.[7][8][4]

Developments and Partnerships

In 2019, Sphere Fluidics in partnership with Peak Analysis and Automation (PAA) introduced Integrated Microplate Handling and Single Cell Analysis Capabilities. The addition of S-LAB to the Cyto-Mine provides researchers with a further streamlined solution for single cell analysis in biopharmaceutical workflows.[9]

On 10 November 2021, Sphere Fluidics in partnership with ClexB gave away 10 CYTRIX microfluidic hydrogel kits containing the novel CYTRIX hydrogel, Pico-Surf™ surfactant and Sphere Fluidics’ Pico-Gen™ double aqueous biochip, giving a plug-and-play system for microfluidic single-cell hydrogel encapsulation, marking the celebration of World Science Day for Peace and Development.[10]

Awards

2013 : ACES Life Science Award[11][5]

2015: UK's top 50 disruptive SMEs by Real Business[12][13]

2017: European Product Innovation Award[2][14]

2020: Queen’s Award for Enterprise for Innovation[15]

References

  1. ^ "Sphere Fluidics Limited Limited". Companies House. Retrieved 21 March 2021.
  2. ^ a b c "Triple success for Cambridge life science pioneers | Business Weekly | Technology News | Business news | Cambridge and the East of England". www.businessweekly.co.uk. Retrieved 2017-12-11.
  3. ^ a b "Sphere Fluidics wins $7 million for development of single cell analysis system - Cambridge Enterprise". Cambridge Enterprise. Retrieved 2017-12-11.
  4. ^ a b c "Sphere Fluidics: biotherapeutics device attracts $7m investment - GOV.UK". www.gov.uk. Retrieved 2017-12-11.
  5. ^ a b c "Re-inventing the test tube: Sphere Fluidics pioneers new approach to analysing cell samples | Science|Business". sciencebusiness.net. Retrieved 2017-12-11.
  6. ^ a b biopharma-reporter.com. "Sphere Fluidics closes $40m funding round". biopharma-reporter.com. Retrieved 2021-11-29.
  7. ^ "Sphere Fluidics, Geneva Biotech Receive €1.6M Grant to Develop DNA Cargo Delivery System". GenomeWeb. Retrieved 2017-12-11.
  8. ^ "TTP Plc and Sphere Fluidics introduce Cyto-Mine Single Cell Analysis System". The Scientist. Retrieved 2017-12-11.
  9. ^ "Sphere Fluidics and PAA Introduce Integrated Microplate Handling and Single Cell Analysis Capabilities". Lab Manager. Retrieved 2021-11-29.
  10. ^ "Sphere Fluidics and ClexBio giving away CYTRIX hydrogel kits". News-Medical.net. 2021-11-12. Retrieved 2021-11-29.
  11. ^ "Sphere Fluidics Wins Award for Academic Spin-Outs Labmate Online". www.labmate-online.com. Retrieved 2017-12-11.
  12. ^ "Sphere Fluidics named one of Britain's most disruptive businesses - Cambridge Enterprise". Cambridge Enterprise. Retrieved 2017-12-11.
  13. ^ "Future 50 retrospective: Innovating big for the future". Real Business. 2017-02-28. Retrieved 2017-12-11.
  14. ^ "Frost & Sullivan Commends Sphere Fluidics for Its Innovative Single-cell Analysis Platform Solution".
  15. ^ "Sphere Fluidics receives Queen's Award for Enterprise". News-Medical.net. 2020-04-21. Retrieved 2021-11-29.