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{{PBB|geneid=26168}}
{{PBB|geneid=26168}}
'''SUMO1/sentrin/SMT3 specific peptidase 3''', also known as '''SENP3''', is a human [[gene]] that, together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by '''B23/nucleophosmin/[[NPM1]]''' and involved in the regulation of '''ribosome biogenesis'''. SENP3 may be regulated by '''Arf-Mdm2-p53''' pathway.<ref name="entrez">{{cite web | title = Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26168| accessdate = }}</ref>
'''SUMO1/sentrin/SMT3 specific peptidase 3''', also known as '''SENP3''', is a human [[gene]] that, together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by '''B23/nucleophosmin/[[NPM1]]''' and involved in the regulation of '''[[ribosome]] biogenesis'''. SENP3 may be regulated by '''Arf-Mdm2-p53''' pathway.<ref name="entrez">{{cite web | title = Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26168| accessdate = }}</ref>


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Revision as of 23:12, 7 January 2009

Template:PBB SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a human gene that, together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regulation of ribosome biogenesis. SENP3 may be regulated by Arf-Mdm2-p53 pathway.[1]

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References

  1. ^ "Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3".

Further reading

Template:PBB Further reading

  • Haindl M, Harasim T, Eick D; et al. (2008). "The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing

". EMBO reports. 9 (3): 273–279. PMID PMC2267381. {{cite journal}}: Check |pmid= value (help); Explicit use of et al. in: |author= (help); Text "doi:10.1038/embor.2008.3" ignored (help); line feed character in |title= at position 123 (help)CS1 maint: multiple names: authors list (link)}}

  • Kuo ML, den Besten W, Thomas MC; et al. (2008). "Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3". Cell Cycle. 7 (21): 3378–87. PMID 18948745. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)}}

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