Talk:Superoxide dismutase: Difference between revisions
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:the existence of a motor neuron disease in individuals who have point mutations in SOD and by the finding that the absence of SOD may lead to a form of [[anemia]]. |
:the existence of a motor neuron disease in individuals who have point mutations in SOD and by the finding that the absence of SOD may lead to a form of [[anemia]]. |
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--[[User:Quarterduck|Quarterduck]] 02:54, 21 Dec 2004 (UTC) |
--[[User:Quarterduck|Quarterduck]] 02:54, 21 Dec 2004 (UTC) |
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== SOD mutations in disease == |
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This statement is unreferenced: |
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"Mutations in SOD1 can cause familial ALS, by a mechanism that is presently not understood, but not due to loss of enzymatic activity or a decrease in the conformational stability of the SOD1 protein." Anyone wish to clarify to what this is referring?[[Special:Contributions/173.8.220.209|173.8.220.209]] ([[User talk:173.8.220.209|talk]]) 23:49, 23 February 2010 (UTC) |
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==Introductory Paragraph== |
==Introductory Paragraph== |
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Revision as of 23:49, 23 February 2010
I am removing that part about delivery systems. Reeks of advertisement and unproven claims. —Preceding unsigned comment added by 24.198.36.244 (talk) 05:45, 6 November 2008 (UTC)
Removed because it's too vague:
- the existence of a motor neuron disease in individuals who have point mutations in SOD and by the finding that the absence of SOD may lead to a form of anemia.
--Quarterduck 02:54, 21 Dec 2004 (UTC)
SOD mutations in disease
This statement is unreferenced: "Mutations in SOD1 can cause familial ALS, by a mechanism that is presently not understood, but not due to loss of enzymatic activity or a decrease in the conformational stability of the SOD1 protein." Anyone wish to clarify to what this is referring?173.8.220.209 (talk) 23:49, 23 February 2010 (UTC)
Introductory Paragraph
Can anyone clarify this statement in the first paragraph?
- One of the exceedingly rare exceptions is Lactobacillus plantarum and related lactobacilli.
Is this supposed to mean that L. plantarum doesn't use SOD specifically for antioxidant defense, or doesn't use SOD at all?
--Scienthomas 18:33, 13 April 2006 (UTC)
- According to the Lactobacillus plantarum entry SOD is not present in that genus.
- apers0n 10:07, 7 May 2006 (UTC)
I found a glitch in the introductory section:
"For the E. coli Fe-SOD: . Fe-SOD can be found in the plastids of plants."
To the best of my knowledge E. coli do not have plastids. Therefore, to make sense it should be reformulated as: "For the E. coli Fe-SOD: Fe-SOD can be found in the cytosol [1] or in the extracellular matrix [2]. In plants: Fe-SOD can be found in the plastids" For celular localization of SOD please see the entries in Brenda database [3], searching for EC 1.15.1.1 (superoxide dismutase) and selecting the organism you are interested in.
1. Beyer W, Imlay J, Fridovich I., Superoxide dismutases in Prog Nucleic Acid Res Mol Biol. 1991;40:221-53. 2. Munkres KD.,Purification of exocellular superoxide dismutases, in Methods Enzymol. 1990;186:249-60. 3.Brenda: The Comprehensive Enzyme Information System, http://www.brenda-enzymes.org/index.php4 —Preceding unsigned comment added by 24.87.53.164 (talk) 15:25, 11 April 2009 (UTC)
Page requires reorganising
(Using Firefox to view page) The image above the text "Structure of the active site of human superoxide dismutase 2" is covering part of the page's main text. The Image should be moved. This may be a problem specific to Firefox. Cs1kh 17:13, 23 July 2007 (UTC)