Talk:Red blood cell

Nuclear DNA

"Erythrocytes in mammals are anucleate when mature, meaning that they lack a cell nucleus and as a result, have no DNA." Should the phrase 'as a result' be removed? It implies that any cell without a nucelus has no genetic material at all. Bacteria have no nuclei but still contain DNA. —Preceding unsigned comment added by 81.110.202.99 (talk) 12:00, 4 January 2009 (UTC)

I removed the "no DNA" part from that sentence. AxelBoldt (talk) 22:15, 26 January 2009 (UTC)

why are they here? Also, only bacteria cells do not have Nuclei —Preceding unsigned comment added by 71.241.236.156 (talk) 20:06, 22 November 2009 (UTC)

=

Do Human erythrocytes contain DNA or don't they? "They contain no nuclei." means very little. It implies that since nuclear DNA is found in the nucleus that they contain only mitrochondrial DNA. Very disappointed in the quality of this article. WIsh I knew enough to fix it.71.31.147.72 (talk) 13:30, 4 January 2012 (UTC)

Nucleated RBCs

It may bhjsdfk.wsfgwk.eqgrt2e worth mentioning that a nucleated RBC is a I have added the article to the category named Respiration. I am now thinking that I should have added it to the sub-category within the Respiration category named Respiratory System. Respiration is something that red blood cells do by taking oxygen from the part of the Respiratory System called the Respiratory Tract to the cells of the body with mitochondrial Dna. Alec - U.K. 17:20, 22 November 2006 (UTC)

Question

Okays, I'm wondering why at the very beginning, second paragraph, it says "Whitney cells..." out of nowhere. There is no indication of the word Whitney before hand and it makes absolutely no sense, whatsoever.

Thanks for catching that. It was vandalism, introduced here. It is now fixed. --Arcadian 22:13, 2 December 2006 (UTC)

I couldn't figure out where to post a new question, but i have one. Did they forget to mention that a human red blood cell contains none of the chromosomes? Or did i miss it? —Preceding unsigned comment added by 76.242.69.33 (talk) 09:45, 18 May 2008 (UTC)

"Erythrocytes in mammals are anucleate when mature, meaning that they lack a cell nucleus and as a result, have no DNA. In comparison, the erythrocytes of nearly all other vertebrates have nuclei; the only known exception being salamanders of the Batrachoseps genus.[7]" —Preceding unsigned comment added by 77.100.4.112 (talk) 17:18, 3 January 2009 (UTC)

Count Count

I've heard the body's entire supply of red blood cells recycles every 6min. True? Trekphiler 08:59, 6 January 2007 (UTC)

No. RBCs have a lifetime of 120 days, so it's not possible. Lennert B 16:00, 9 May 2007 (UTC)

Hey,

What is the average RBC count for human?

-B —Preceding unsigned comment added by 203.99.195.64 (talk) 09:54, August 24, 2007 (UTC)

about 25 trillion--Amaher (talk) 01:20, 20 January 2010 (UTC)

Here and many other locations on the internet say that a red blood "cycle of circulation" is 20 seconds. What does that mean? releasing oxygen atoms? or a circuit around the body from when it leaves the heart to when it comes back again? The 3 references are to books I don't have access to. — Preceding unsigned comment added by Idji (talk • contribs) 12:40, 18 December 2011 (UTC)

Vertebrate erythrocytes

There seems to be something wrong with this section. A paragraph intersects with a picture and makes the page really wide. I don't know how to fix this, but I just wanted to note it.Xasz 01:34, 9 October 2007 (UTC)

Homework

How much percent of 1 liter of blood are RBC's —Preceding unsigned comment added by 70.123.158.149 (talk) 22:56, 28 February 2008 (UTC)

ffgg —Preceding unsigned comment added by 207.190.178.28 (talk) 16:53, 7 March 2008 (UTC)

about 40-50% depending on whether your man or woman--Amaher (talk) 01:20, 20 January 2010 (UTC)

shnify

very shnify today bahh shnify —Preceding unsigned comment added by 91.107.23.122 (talk) 11:26, 17 May 2008 (UTC)

what are blood cells where do they come from. are they of live are we from space. if where from space did god. make us or did blood cells make us. are blood cells rael are we rael. are we just in a deam. —Preceding unsigned comment added by 207.157.30.66 (talk) 14:58, 21 May 2008 (UTC)

what are blood cells

blood cells are thing that help your body live. red blood cells send air through the air gos to your lungs. and to your hart. white blood cells. they kill germs and they multiply and they can stop infections. platelets help your body stop bleeding when you cut your or a wound. platelets clump togther as soon as you start to bleed. the sticky clump of platelets traps red blood cells. —Preceding unsigned comment added by 207.157.30.66 (talk) 17:55, 22 May 2008 (UTC)

A dubious desire to fork this page

Red Blood Cells (note caps) is the proper name (in the US) for approximately 200 ml of erythrocytes in storage solution used in transfusion medicine. This could easily be a separate article, since it's essentially used as a medication. I'm not sure if this proper name is used globally. Should this information be added here, should the page be forked? Red Blood Cells (transfusion medicine)? The same issue will come up with Platelets, though the fork there couldn't be based on capitalization. Somedumbyankee (talk) 14:15, 19 June 2008 (UTC)

I'll add the information to this article for now; I suppose a separate article could also be written if there's enough material for it. AxelBoldt (talk) 13:23, 28 July 2008 (UTC)

Even if the page isn’t split, I think it should be renamed to Erythrocytes with a redirect from Red blood cells --ITasteLikePaint (talk) 03:39, 10 February 2009 (UTC)

Hemoglobin's are not molecules; they are proteins. —Preceding unsigned comment added by TheGovernor11 (talk • contribs) 06:59, 3 October 2008 (UTC)

Hemoglobin

{{editsemiprotected}} Hemoglobins are not molecules; they are proteins.

TheGovernor11 (talk) 07:00, 3 October 2008 (UTC)

Y In theory, it's a biomolecule, which includes heteromeric proteins. haz (talk) 07:51, 3 October 2008 (UTC)

red blood cell

need more info —Preceding unsigned comment added by 78.145.71.151 (talk) 09:00, 8 October 2008 (UTC)

We need more info on what you need more info about. If you have a specific question, Wikipedia:Reference desk/Science may be able to help. SDY (talk) 12:41, 8 October 2008 (UTC)

Erythrocyte shape

This Wikipedia article states: Mammalian erythrocytes are biconcave disks: flattened and depressed in the center, with a dumbbell-shaped cross section. This shape (as well as the loss of organelles and nucleus) optimizes the cell for the exchange of oxygen with its surroundings.

However, the shape of the red blood cell does not actually serve to optimize the cell for oxygen exchange. Since it is being squished through capillaries, it loses its shape when exchanging oxygen. Instead, it has been suggested that the biconcave shape of erythrocytes serves to maximize laminar flow and minimize platelet scatter, thereby suppressing atherogenesis. Source: The human erythrocyte has developed the biconcave disc shape to optimize the flow properties of the blood in the large vessels, C. Uzoigwe, 2006
Could someone edit that portion of the article?
Studytilidie (talk) 01:56, 14 October 2008 (UTC) == blood cells are red they are red cause of our insides

==

OR

he most kind of cells ARE RED CELLS THEY PUT OFF MOST OF THE HEAT IN YOUR BODYWIGHT CELL CANPUT OFF IF YOUR ARE #REDIRECT [[RED CELLS

Is this comment intended to change or add to content already in the article? Wisdom89 _{(T / ^C)} 14:43, 22 September 2009 (UTC)

lifetime determinants, oxidative issues and species or specifics of hemoglobin structure

this also comes up with dogs and cats that seem particularly sensitive but these refs should outline some issues,

Sivilotti, ML (2004). "Oxidant stress and haemolysis of the human erythrocyte". Toxicological reviews. 23 (3): 169–88. PMID 15862084.{{cite journal}}: CS1 maint: date and year (link)

Matarrese, P; Pietraforte, D; Gambardella, L; Vona, R; Maccaglia, A; Minetti, M; Malorni, W (Mar-2005). "Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases". The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19 (3): 416–8. doi:10.1096/fj.04-2450fje. PMC 10.1096/fj.04-2450fje. PMID 15650007. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link) CS1 maint: unflagged free DOI (link)

Denicola, A; Lissi, E; Freeman, BA; Rubbo, H; Radi, R (11-Jan-2002). "Diffusion of nitric oxide into low density lipoprotein". The Journal of biological chemistry. 277 (2): 932–6. doi:10.1074/jbc.M106589200. PMC 10.1074/jbc.M106589200. PMID 11689557. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link) CS1 maint: unflagged free DOI (link)

Nerdseeksblonde (talk) 02:54, 15 November 2009 (UTC)

Kantar, A; Curatola, G; Fiorini, R (1992). "Alterations in erythrocyte membrane fluidity in children with trisomy 21: a fluorescence study". Biology of the cell / under the auspices of the European Cell Biology Organization. 75 (2): 135–8. PMID 1393150.{{cite journal}}: CS1 maint: date and year (link)

Fernández, E; Martínez, G (Sep-1987). "Phototoxicity from nalidixic acid: oxygen dependent photohemolysis". Il Farmaco; edizione scientifica. 42 (9): 681–90. PMID 3691790. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

Thornalley, PJ (Dec-1985). "Monosaccharide autoxidation in health and disease". Environmental health perspectives. 64: 297–307. PMID 3007096. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

References repeated in the ref list

How can I make references added not repeat in the ref list, so they only appear once? In case anyone is interested here is my bibliography on the subject: http://www.zotero.org/rogeriopfm/items/collection/1100893 —Preceding unsigned comment added by Rogeriopfm (talk • contribs) 22:08, 15 November 2009 (UTC)

Blood Group Confusion

In the section "History" it says: "A year later Alfred von Decastello and Adriano Sturli, two colleagues of Landsteiner, identified a fourth blood group - AB - the serum of which causes both A and B red cells to agglutineate."

I think this is wrong. The serum of somebody with blood group AB doesn't cause anybody's cells to agglutinate, because it doesn't contain antibodies against any blood group. Could somebody with more Wikipedia experience please confirm this and change the article accordingly! Thanks —Preceding unsigned comment added by 188.45.151.136 (talk) 17:52, 7 January 2010 (UTC)

I've removed the last part of the sentence, I don't think it requires any further classification, as the section is purely history-related. Besides, if AB serum caused agglutination, they wouldn't be able to accept any other blood than AB, which is incorrect. Perspeculum (talk) 13:27, 8 January 2010 (UTC)

Interaction with glucose / glycated hemoglobin

I would like to see an explanation of how glucose interacts with red blood cells.

This article says: "Oxygen can easily diffuse through the red blood cell's cell membrane."

The diabetes A1C test measures the ratio of glycated hemoglobin - glucose binding to hemoglobin. http://en.wikipedia.org/wiki/Glycated_hemoglobin

I assume that glucose (larger than O) must also enter the cell before binding to the hemoglobin proteins. Do RBCs actually utilize glucose as other cells do?

What's the purpose of merely binding to glucose? Why would this happen if glucose is needed for energy?

In most other cells, insulin is required for glucose to enter the cell. Is that true here? — Preceding unsigned comment added by Biotech99 (talk • contribs) 16:46, 7 June 2011 (UTC)

Viruses and Red Blood Cells

Extreme exceptions, but the statement about it being impossible for viruses to infect red blood cells is too strong: This paper discusses viruses that get in early while there is still a nucleus (and therefore the red blood cell matures with the virus inside) http://cancerres.aacrjournals.org/content/31/6/841.full.pdf

This paper discusses genetic engineered mice whose red cells trick the virus into infecting them (but the virus then cannot proceed because of lack of nucleus):

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200307/ — Preceding unsigned comment added by 81.98.248.70 (talk) 00:01, 5 November 2011 (UTC)

I concur with this sentiment. The ability of a virus to INFECT a cell is based on the glycoproteins that a certain cell carries on its lipid membrane which act as ligands for the viral protein receptors, NOT on whether a particular cell has nuclei or not. Without nuclei, the viruses might not be able to REPLICATE (distinct from INFECTION) in the cell - but of course, if the RBC is still ennucleated (as is the case in the bone marrow), it can still replicate there too. Please correct this. — Preceding unsigned comment added by 74.110.239.183 (talk) 09:57, 3 December 2011 (UTC)