Tributyrin: Difference between revisions
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'''Butyrin''', also known as '''tributyrin''', is a [[triglyceride]] naturally present in [[butter]]. It is an [[ester]] composed of [[butyric acid]] and [[glycerol]].<ref name=Merck/> Among other things, it is used as an ingredient in making [[margarine]]. It is |
'''Butyrin''', also known as '''tributyrin''', is a [[triglyceride]] naturally present in [[butter]]. It is an [[ester]] composed of [[butyric acid]] and [[glycerol]].<ref name=Merck/> Among other things, it is used as an ingredient in making [[margarine]]. It is present in butter and can be described as a liquid [[fat]] with an acrid taste. |
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Tributyrin is also used in microbiological laboratories to identify the bacterium ''Moraxella catarrhalis''. <ref>{{Cite journal |
Tributyrin is also used in microbiological laboratories to identify the bacterium ''Moraxella catarrhalis''. <ref>{{Cite journal |
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Revision as of 14:57, 30 November 2012
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| Names | |
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| IUPAC name
1,3-Di(butanoyloxy)propan-2-yl butanoate
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| Other names
Tributyrin
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.000.410 |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C15H26O6 | |
| Molar mass | 302.367 g·mol−1 |
| Appearance | Oily liquid with bitter taste[1] |
| Density | 1.032 g/cm3[1] |
| Melting point | −75 °C (−103 °F; 198 K) |
| Insoluble[1] | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Butyrin, also known as tributyrin, is a triglyceride naturally present in butter. It is an ester composed of butyric acid and glycerol.[1] Among other things, it is used as an ingredient in making margarine. It is present in butter and can be described as a liquid fat with an acrid taste.
Tributyrin is also used in microbiological laboratories to identify the bacterium Moraxella catarrhalis. [2]
Tributyrin is a stable and rapidly absorbed prodrug of butyric acid which enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells.[3]
References
- ^ a b c d e f Budavari, Susan, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123
- ^ Pérez, José L. (1990). "Butyrate esterase (4-methylumbelliferyl butyrate) spot test, a simple method for immediate identification of Moraxella (Branhamella) catarrhalis corrected" (PDF Reprint). Journal of Clinical Microbiology. 28 (10). Washington, DC: American Society for Microbiology: 2347–2348. ISSN 1098-660X. PMC 268174. PMID 2121784.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help) - ^ Gaschott, Tanja (2001). "Tributyrin, a Stable and Rapidly Absorbed Prodrug of Butyric Acid, Enhances Antiproliferative Effects of Dihydroxycholecalciferol in Human Colon Cancer Cells". The Journal of Nutrition. 131 (6). Bethesda, MD: The American Society for Nutritional Sciences: 1839–1843. ISSN 1541-6100. PMID 11385076. Retrieved 2009-08-17.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help)