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'''NG2 glia''' is a type of [[macroglia]] found in the [[central nervous system]], which is distinct from [[astrocytes]] and [[oligodendrocytes]].<ref>{{cite journal|last1=Raff|first1=MC|last2=Miller|first2=RH|last3=Noble|first3=M|year=1983|title=A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium|journal=Nature|volume=303|pages=390–396|doi=10.1038/303390a0|pmid=6304520|issue=5916}}</ref> They get their name from the expression of [[NG2 proteoglycan]] on their surface. Although their exact function is unknown, they are found engulfing [[synapses]] and express receptors specific for the synapses.<ref>{{pmid|10088675}}</ref> NG2 [[glia]] were believed to be the precursors of oligodendrocytes, but recent evidence suggests that they have distinct functions and divide very slowly.<sup>[Citation Needed]</sup> From an evolutionary point of view, the NG2 glia attained more complexity in the mammals and primates.
'''NG2 glia''' is a type of [[macroglia]] found in the [[central nervous system]], which is distinct from [[astrocytes]] and [[oligodendrocytes]].<ref>{{cite journal|last1=Raff|first1=MC|last2=Miller|first2=RH|last3=Noble|first3=M|year=1983|title=A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium|journal=Nature|volume=303|pages=390–396|doi=10.1038/303390a0|pmid=6304520|issue=5916}}</ref> They get their name from the expression of [[NG2 proteoglycan]] on their surface. Although their exact function is unknown, they are found engulfing [[Nodes of Ranvier]].<ref>{{pmid|10088675}}</ref> NG2 [[glia]] were believed to be the precursors of [[oligodendrocytes]], but recent evidence suggests that they have distinct functions and divide very slowly.<ref>{{pmid|19096367}}</ref> From an evolutionary point of view, the NG2 glia attained more complexity in the mammals and primates.


==References==
==References==

Revision as of 16:14, 11 April 2013

NG2 glia is a type of macroglia found in the central nervous system, which is distinct from astrocytes and oligodendrocytes.[1] They get their name from the expression of NG2 proteoglycan on their surface. Although their exact function is unknown, they are found engulfing Nodes of Ranvier.[2] NG2 glia were believed to be the precursors of oligodendrocytes, but recent evidence suggests that they have distinct functions and divide very slowly.[3] From an evolutionary point of view, the NG2 glia attained more complexity in the mammals and primates.

References

  1. ^ Raff, MC; Miller, RH; Noble, M (1983). "A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium". Nature. 303 (5916): 390–396. doi:10.1038/303390a0. PMID 6304520.
  2. ^ PMID 10088675
  3. ^ PMID 19096367