Talk:Parkinsonism

Cerebellar thoracic outlet syndrome

I wasn't aware that thoracic outlet syndrome could cause parkinsonism, as this isn't a typical finding. Perhaps this could be better referenced in the article. Andrew73 00:25, 30 October 2006 (UTC):It is only a particular type of TOS that can cause it - Cerebellar Thoracic Outlet Syndrome

Journal of Cardiovascular Surgery (Toriono) [1996] 37 (6 Supplement 1) : 155-166 (E.I.Fernandez Noda, J.Nunez-Arguelles, J.Perez Fernandez, J.Castillo, M.Perez Izquierdo, H.Rivera Luna)

Rinsho Kyobu Geka [1987] 7 (3) : 271-275 (E.I.Noda Fernandez, A.Lugo, E.Berrios, J.R.del Valle, F.Alvardo, M.S.Buch, J.P.Fernandez)

--Professor Rizzo Naudi 00:54, 30 October 2006 (UTC)

This is far from established. The two papers that come up on PubMed are from the same Puerto Rican research group and no attempts seem to have been made to verify its existence, let alone replicate the interventions they propose.

Harrisson's "Principles of Internal Medicine" 16th ed page 2408 gives a fairly exhaustive list for the differential of Parkinsonism. CTOS is not in the list. If something is not in a highly authoritative textbook, I suspect it may not be worthy of inclusion in Wikipedia. JFW | T@lk 21:02, 31 October 2006 (UTC)

Article too "list-y"

I'd like to see the differential diagnosis section re-written in prose - any volunteers? If not, I'll take a stab at it in the next week or so.... -- MarcoTolo 01:40, 9 June 2007 (UTC)

References

I agree that the existing references aren't the best ones out there, but perhaps it may be reasonable to leave them in place for now until better ones are found. Andrew73 20:08, 11 June 2007 (UTC)

If there are particular references that folks feel less-than-comfortable with, I'm not particularly attached to any of the refs - feel free to replace them (textbooks, peer-reviewed, etc). -- MarcoTolo 20:21, 11 June 2007 (UTC)

Hydrocephalus

Symptoms of Parkinson's Disease can often occur simultaneously with Hydrocephalus [1,2,3], and can be due to the effects of Hydrocephalus [2,4,5,6]. The Parkinson's Disease symptoms may be caused by increased intracranial pressure reducing blood flow to the basal ganglia where dopamine is produced [6].

[1] Journal of neurology, neurosurgery and psychiatry [2001] 70 (3) : 289-297 (H.Stolze, J.P.Kuhtz-Buschbeck, H.Drucke, K.Johnk, M.Illert, G.Deuschl)

[2] Movement Disorders [1997] 12 (1) : 52-60 (J.K.Krauss, J.P.Regel, D.W.Droste, M.Orszagh, J.J.Borremans, W.Vach)

[3] Movement Disorders [1994] 9 (5) : 508-520 (T.Curran, A.E.Lang)

[4] Movement Disorders [1986] 1 (1) : 59-64 (J.Jankovic, M.Newmark, P.Peter)

[5] Canadian Journal of Neurological Science [1985] 12 (3) : 255-258 (L.Berger, S.Gauthier, R.Leblanc)

[6] Pediatric Neurology [1988] 4 (2) : 117-119 (E.Shahar, R.Lambert, P.A.Hwang, H.J.Hoffman)

Tojo, we've discussed this before. It is rare and not listed in major textbooks. JFW | T@lk 06:26, 24 July 2007 (UTC)

parkinsons vs parkinsonism

What is the difference between parkinsons disease and parkinsonism? I am a CNA and I currently work with a patient who was diagnosed with parkinsonism 2 years ago. We go to a support group once a month. But I haven't quite grasped the difference between the two. Can you help me understand the difference? —Preceding unsigned comment added by 72.184.128.15 (talk) 02:01, 2 January 2010 (UTC)

I believe that pseudo parkinsonism is properly used to describe motor symptoms, such as EPS, that resemble pd in some respects but are not necessarily due to the same underlying neurological deficit ie SN dopaminergic neuron death. this is supported by the fact that the two conditions respond to treatments differently. I will look for a reference that claimed that drug induced pseudo parkinsonism does not respond to anti-cholinergics. consider that there are multiple subsystems of the SN that are not all purely dopaminergic, such as the striatal -> GPe/GPi gabaergic pathways, and the STN which has afferent gaba pathways and efferent glutamatergic pathways and appears to regulate a difference in basal tone between the GPi and GPe. Beware of the (oh so underpaid) Status Quo which will defend to the death the right to stone wall patients who complain about EPS with the assertion that it was their own failing dopamine systems all along and that the recent overdose of haliperidol had nothing to do with the sudden emergence of permanent EPS. This is a hotspot of contemporary medical fraud, Systematic underreporting of EPS, because ER mds do not want to lose the option of miniDEEPSLEEP_tm therapy, ie knocking a patient out for 3days with 20mg+ of haliperidol. oh look how peaceful they look, no "agitation" (were they brought in by police and really had quite reasonable justification for agitation) at all... pity when they get discharged and enough halflifes later the EPS begins they're going to be permanently agitated for the rest of their lives.

do you want to be the Emergency Medical Doctor to give a patient in their 20's permanent agitation for life, just to keep the average discharge time down. We need more references to the actual difference between Neuroleptic induced pseudo parkinsonism and true parkinsons. We also need accompanying evidence that no possible benefit of initial high dose haliperidol can justify the substantial risk (50%+) of permanent EPS.

Parkinson's is not specific for disease or syndrome. Parkinsonism is specific for syndrome. — Preceding unsigned comment added by Doctorlynn@hotmail.com (talk • contribs) 00:23, 15 April 2013 (UTC) Using the term Parkinsonism, is describing someone with the signs and symptoms of Parkinsons disease. However there are many diseases that present just like Parkinson disease and if these diseases are not considered, then a misdiagnosis of Parkinson disease might happen. Because numerous diseases present with parkinsonism, there needs to be a list. If you do not like lists, then that is your personal choice. However if someone diagnosed me with Parkinsons disease, I might want to know if there was something else that was missed. I would like to have a list of diseases that present in the same or similar manner as Parkinson disease. A list of diseases causing Parkinsonism 74.131.58.49 (talk) 19:19, 19 April 2013 (UTC)CommonMed] = 74.131.58.49 (talk) 19:19, 19 April 2013 (UTC)DAL — Preceding unsigned comment added by 74.131.58.49 (talk) 19:07, 19 April 2013 (UTC)