Leucines: Difference between revisions

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The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert-leucine and norleucine. Being compared with the four butanols, they could be classified as butyl-substituted glycines; they represent all four possible variations.

Leucine and isoleucine belong to the proteinogenic amino acids; the others are non-natural.

Including the stereoisomers, six further isomers could be added: D-leucine, D-isoleucine, L-allo-isoleucine, D-allo-isoleucine, D-tert-leucine and D-norleucine.

Cycloleucine could be classified as a cyclic derivate of norleucine. With a cyclopentane-ring, it has two hydrogen atoms fewer and thus is not an isomer. The α-carbon atom is not a stereocenter.

Leucines
Name	L-Leucine	L-Isoleucine	L-tert-Leucine (Terleucine)	L-Norleucine	Cycloleucine
Other names	2-Amino-4-methylpentanoic acid, Isobutylglycine	2-Amino-3-methylpentanoic acid, sec-Butylglycine	2-Amino-3,3-dimethylbutanoic acid, tert-Butylglycine	2-Amino-hexanoic acid, n-Butylglycine	1-Amino-cyclopentane-1-carboxylic acid
Structure
CAS-number	61-90-5	73-32-5	20859-02-3	327-57-1	52-52-8
PubChem	CID 6106 from PubChem	CID 791 from PubChem	CID 164608 from PubChem	CID 21236 from PubChem	CID 2901 from PubChem
Molecular formula	C₆H₁₃NO₂				C₆H₁₁NO₂
Molar mass	131.18 g/mol				129.16 g/mol

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 Including the stereoisomers, six further isomers could be added: <small>D</small>-leucine, <small>D</small>-isoleucine, <small>L</small>-''allo''-isoleucine, <small>D</small>-''allo''-isoleucine, <small>D</small>-''tert''-leucine and <small>D</small>-norleucine.
-[[Cycloleucine]] could be classified as a cyclic derivate of [[norleucine]]. With a [[cyclopentane]]-ring, it has two hydrogen atoms less and thus is not an isomer. The α-carbon atom is not a stereocenter.
+[[Cycloleucine]] could be classified as a cyclic derivate of [[norleucine]]. With a [[cyclopentane]]-ring, it has two hydrogen atoms fewer and thus is not an isomer. The α-carbon atom is not a stereocenter.
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