Mcr1: Difference between revisions
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{{about|the yeast gene|the prokaryote gene|MCR-1}} |
{{about|the yeast gene|the prokaryote gene|MCR-1}} |
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'''MCR1''' is a [[gene]] found in yeast. It is used to understand [[cell cycle checkpoint]]s.<ref name="ent">{{cite journal |author=Yin L, Locovei AM, D'Urso G |title=Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation |journal=Mol. Biol. Cell |volume=19 |issue=10 |pages=4374–82 |date=October 2008 |pmid=18667534 |pmc=2555949 |doi=10.1091/mbc.E08-01-0020 |url=http://www.molbiolcell.org/cgi/pmidlookup?view=long&pmid=18667534}}</ref> Researchers are working to find a way to use this [[gene]] to create [[anti-cancer drugs]].<ref name="ent"/> |
'''MCR1''' is a [[gene]] found in [[yeast]]. It is used to understand [[cell cycle checkpoint]]s.<ref name="ent">{{cite journal |author=Yin L, Locovei AM, D'Urso G |title=Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation |journal=Mol. Biol. Cell |volume=19 |issue=10 |pages=4374–82 |date=October 2008 |pmid=18667534 |pmc=2555949 |doi=10.1091/mbc.E08-01-0020 |url=http://www.molbiolcell.org/cgi/pmidlookup?view=long&pmid=18667534}}</ref> Researchers are working to find a way to use this [[gene]] to create [[anti-cancer drugs]].<ref name="ent"/> |
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== Function == |
== Function == |
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Revision as of 18:26, 18 December 2015
MCR1 is a gene found in yeast. It is used to understand cell cycle checkpoints.[1] Researchers are working to find a way to use this gene to create anti-cancer drugs.[1]
Function
The most common function is found during the cell cycle when mutations occur because it becomes activated without phosphorylation and turns on Cds1.[2] It also works with Cdk1 to get rid of the mutations that occur. If MCR 1 is not present in the cell these check points do not work properly.[1]
References
- ^ a b c Yin L, Locovei AM, D'Urso G (October 2008). "Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation". Mol. Biol. Cell. 19 (10): 4374–82. doi:10.1091/mbc.E08-01-0020. PMC 2555949. PMID 18667534.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ "MCR1 Mcr1p [Saccharomyces cerevisiae]". Entrez Gene. National Center for Biotechnology Information.