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  • Thumbnail for Hormesis
    Hormesis is a two-phased dose-response relationship to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts...
    30 KB (3,238 words) - 20:49, 7 June 2024
  • DoseResponse is a quarterly peer-reviewed scientific journal covering research on the dose-response relationship, especially hormesis. It was established...
    3 KB (182 words) - 00:15, 26 April 2023
  • Thumbnail for Isotonic regression
    x , y {\displaystyle x,y} has been applied to estimating continuous dose-response relationships in fields such as anesthesiology and toxicology. Narrowly...
    10 KB (1,439 words) - 01:07, 4 October 2024
  • Thumbnail for Linear no-threshold model
    The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced...
    39 KB (4,584 words) - 02:24, 25 July 2024
  • criteria intended to protect the health of consumers. The concept of a dose-response relationship dates back to as 1493 but its modern usage reaches to the...
    9 KB (1,288 words) - 00:39, 3 June 2024
  • Thumbnail for Toxicology
    animal testing for cosmetics in 2013. Most chemicals display a classic dose response curve – at a low dose (below a threshold), no effect is observed.: 80 ...
    35 KB (3,851 words) - 19:42, 19 July 2024
  • Thumbnail for 4-DAMP
    acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists. "4-DAMP". Sigma-Aldrich. Zhu, MH; Sung, IK;...
    3 KB (190 words) - 12:49, 1 March 2022
  • Thumbnail for Receptor antagonist
    agonists, and partial agonists. In functional antagonist assays, a dose-response curve measures the effect of the ability of a range of concentrations...
    33 KB (3,845 words) - 01:47, 19 August 2024
  • Thumbnail for Hill equation (biochemistry)
    The Hill equation (for response) is important in the construction of dose-response curves. The Hill equation is commonly expressed in the following ways...
    30 KB (3,330 words) - 13:07, 4 October 2024
  • Thumbnail for Etacrynic acid
    diuretic drugs such as furosemide is that it has a significantly steep dose-response curve, which means the drug's dosing is very important as small variance...
    14 KB (896 words) - 17:55, 29 July 2024
  • Thumbnail for Radiation hormesis
    limitations" with the use of hormesis in general as the "principal dose-response default assumption in a risk assessment process charged with ensuring...
    55 KB (6,726 words) - 11:12, 27 June 2024
  • From All Causes, Cardiovascular Disease, and Cancer: A Dose-Response Meta-Analysis". American Journal of Epidemiology. 180 (8): 763–775. doi:10.1093/aje/kwu194...
    33 KB (2,923 words) - 14:56, 4 October 2024
  • Thumbnail for Piretanide
    high-ceiling diuretics such as furosemide and bumetanide found a more suitable dose/response rate (regression line) and a more favourable sodium/potassium excretion...
    5 KB (309 words) - 12:56, 18 September 2024
  • Thumbnail for Hydromorphinol
    respiratory depression, but is twice as potent as morphine and has a steeper dose-response curve and longer half-life. It is used in medicine as the bitartrate...
    6 KB (449 words) - 14:19, 8 February 2024
  • the activity is generally dosage-dependent, which is investigated via dose-response curves. Further, it is common to have effects ranging from beneficial...
    5 KB (604 words) - 02:36, 28 June 2024
  • Thumbnail for Agonist
    potency, in determining the usefulness of a drug. Allosteric modulator Dose response curve Excitatory postsynaptic potential Functional selectivity Intrinsic...
    14 KB (1,622 words) - 03:21, 4 September 2024
  • drug barely adequate to produce a biological effect in an animal. In dose-response assessment, the term ‘threshold dose’ is refined into several terminologies...
    23 KB (2,910 words) - 06:26, 27 September 2023
  • other organisms by means of meta-analysis. Main goal is to establish dose-response relationships of a wide range of phenotypic traits for a large set of...
    4 KB (545 words) - 11:45, 30 October 2023
  • Stokes GS (1976). "Prazosin: the first-dose phenomenon". British Medical Journal. 2 (6047): 1293–4. doi:10.1136/bmj.2.6047.1293. PMC 1689975. PMID 793676...
    4 KB (428 words) - 06:47, 8 November 2023
  • Thumbnail for Pharmacodynamics
    speaking of PK/PD models). Pharmacodynamics places particular emphasis on doseresponse relationships, that is, the relationships between drug concentration...
    19 KB (2,225 words) - 21:08, 29 May 2024
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