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between the dose needed for the desired effect and the dose that produces unwanted and possibly dangerous side-effects (measured by the TD50, the dose that...14 KB (1,622 words) - 03:21, 4 September 2024
dose-finding experiments is to estimate the strength of treatment (i.e., the "dose") that would trigger the "1" response a pre-specified proportion of the...26 KB (4,352 words) - 16:50, 22 April 2024- intravascular formulation. AUC is used because AUC is proportional to the dose that has entered the systemic circulation. Bioavailability of a drug is...22 KB (2,749 words) - 10:52, 1 November 2024
- occur after an initial dose or after a series of small doses. Increasing the dose of the drug may be able to restore the original response. Tachyphylaxis...13 KB (1,346 words) - 22:19, 3 November 2024
- be safe due to radiation shielding. After one half-life of 5.27 years, the dose rate in the affected area would be 5 Sv/hour. At this dose rate, a person...18 KB (2,106 words) - 06:42, 17 October 2024
- based on the symptoms. Methods of prevention include gradually decreasing the dose among those who wish to stop, though it is possible for symptoms to occur...28 KB (2,803 words) - 21:55, 13 October 2024
serious adverse events include muscle twitching, tremors, and convulsions. The dose to treat barbiturate intoxication or carbon dioxide narcosis in adults...3 KB (228 words) - 08:02, 8 January 2024
those who survive are managed as usual. Short-term outcomes depend on the dose exposure. ARS is generally rare. A single event can affect a large number...65 KB (6,761 words) - 19:57, 14 October 2024
suicidal thoughts, hallucinations, and angioedema. Rapid decreasing of the dose may result in withdrawal. Eszopiclone is classified as a nonbenzodiazepine...28 KB (2,704 words) - 02:21, 4 November 2024- is delivered as a unit. The greater the quantity delivered, the larger the dose. Doses are most commonly measured for compounds in medicine. The term is...23 KB (2,754 words) - 20:25, 30 September 2024
steroids such as prednisone or prednisolone. Once symptoms have resolved, the dose is decreased by about 15% per month. Once a low dose is reached, the taper...33 KB (3,231 words) - 05:22, 25 October 2024- for clinical indications of an approved drug, TI refers to the ratio of the dose of the drug that causes adverse effects at an incidence/severity not compatible...25 KB (3,218 words) - 19:35, 11 October 2024
respectively. The dose of FE 200665 required to produce motor impairment (measure of CNS penetration) was 548 times higher than the dose required for antinociceptive...4 KB (282 words) - 02:51, 21 October 2021
and a piston or plunger to inject the dose. Some pens, including most insulin pens, include dials to adjust the dose of the injection before each administration...27 KB (3,140 words) - 17:25, 26 July 2024- contaminate foods. MID was defined as the number of microorganisms ingested (the dose) from which a pathology is observed in the consumer. For example, to cause...9 KB (1,288 words) - 00:39, 3 June 2024
the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists. "4-DAMP". Sigma-Aldrich. Zhu, MH; Sung...3 KB (195 words) - 02:52, 26 October 2024
by blocking K+ channels and is considered a class III antiarrhythmic. The dose is 5–10 mg/kg and side effects are high blood pressure followed by low...7 KB (625 words) - 04:33, 18 September 2024
4–6 hours and after 24 hours with the aid of a scintillation counter. The dose is typically 0.15–0.37 MBq (4–10 μCi) of 131I iodide, or 3.7–7.4 MBq (100–200...4 KB (434 words) - 07:08, 7 May 2024
pressure. There is a high risk of withdrawal syndrome which may occur if the dose is decreased or the medication is completely stopped. It is unclear if...18 KB (1,425 words) - 12:15, 11 November 2024
measures of potency, such as EC50 for excitatory drugs. EC50 represents the dose or plasma concentration required for obtaining 50% of a maximum effect...10 KB (1,084 words) - 20:25, 28 August 2024
- substitution of the internal use of iron, ( limaille porphyrisée, ) in the dose of a “gros" daily, under the form of opiate, with tonics. 1858, Transactions
- diarrhoea, weakened circulation, etc., and always with beneficial results. The dose of morphia injected varied from one-twelfth to one-half of a grain. According
- write a bill, Of which you need not read one letter, The worse the scrawl, the dose the better. For if you knew but what you take, Though you recover, he must
- evidence points to an increased risk that is approximately proportional to the dose received. Radiologists and radiologic technologists are among the earliest