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Christopher K. Glass

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Christopher Kevin Glass (Ph.D., M.D.) (born 1955, California, USA) is a biophysicist, holding the titles of Distinguished Professor of Cellular and Molecular Medicine and Distinguished Professor of Medicine at the University of California, San Diego [1] He works on the molecular mechanisms that control macrophage functions in health and disease.

Glass majored in Biophysics at the University of California, Berkeley (1977) and received M.D. and Ph.D. degrees from the University of California, San Diego (1984). He performed internship and residency training in internal medicine at Brigham and Women's Hospital in Boston (1985) before returning to UC San Diego for fellowship training in Endocrinology and Metabolism (1989).   He became one of the founding members of the Department of Cellular and Molecular Medicine [2] In 1992 he was appointed Assistant Professor of Medicine at UCSD, and promoted to Associate Professor in 1995, full professor in 1999, and Distinguished Professor in 2018 [2]

Glass is a member of the American Academy of Arts and Sciences,[3] the National Academy of Medicine,[4] and the National Academy of Sciences. [5]

Research Interests

Recent work from the laboratory reported the importance of tissue-specific signals in establishing the diverse macrophage phenotypes observed in different organs including microglia, the major macrophage population in the brain. [6]

Awards and Honors

  • 1989 Wilson S. Stone Award for the M.D. Andersen Cancer Center[7]
  • 2008 Honorary Doctorate of Medicine, University of Linköping, Sweden
  • 2014 Election to American Academy of Arts and Sciences[3]
  • 2015 Election to National Academy of Medicine (formerly Institute of Medicine)[4]
  • 2017 Election to National Academy of Sciences[5]

Most cited Publications

[8][9]

  • Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.[10] Mol Cell. 2010 38:576-89. PMID: 20543837 PMCID: PMC2898526 According to Google Scholar, it has been cited 6487 times. [11]
  • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor gamma is a negative regulator of macrophage activation.[12] Nature 391:79-82, 1997. PMID: 9422508 According to Google Scholar, this article has been cited 4118 times [11]
  • Glass CK, Witztum, JL. Atherosclerosis: the road ahead. [13] Cell 2001 104 (4) 503-516. PMID: 11239408 According to Google Scholar, it has been cited 3831 times. [11]

References

  1. ^ "Department of Cellular and Molecular Medicine". UC San Diego School of Medicine.
  2. ^ a b Glass, Christopher K. "Biographical sketch" (PDF). OMB. Retrieved March 30, 2020.
  3. ^ a b AAAS Member profile https://www.amacad.org/person/christopher-k-glass
  4. ^ a b NAM Member profile [1]
  5. ^ a b NAS Member profile http://www.nasonline.org/member-directory/members/20038050.html
  6. ^ Gosselin, David; Skola, Dylan; Coufal, Nicole G.; Holtman, Inge R.; Schlachetzki, Johannes C. M.; Sajti, Eniko; Jaeger, Baptiste N.; O'Connor, Carolyn; Fitzpatrick, Conor; Pasillas, Martina P.; Pena, Monique; Adair, Amy; Gonda, David D.; Levy, Michael L.; Ransohoff, Richard M.; Gage, Fred H.; Glass, Christopher K. (June 23, 2017). "An environment-dependent transcriptional network specifies human microglia identity". Science. 356 (6344): eaal3222. doi:10.1126/science.aal3222c. PMC 5858585. PMID 28546318 – via PubMed.Science. 2017 doi:10.1126/science.aal3222. PubMed PMID: 28546318. (>480 citations)
  7. ^ "M. D. Anderson Cancer Center - Current Research/Awards". www3.mdanderson.org.
  8. ^ "Highly Cited Researchers (h>100) according to their Google Scholar Citations public profiles | Ranking Web of Universities: Webometrics ranks 30000 institutions". www.webometrics.info.
  9. ^ "glass ck". scholar.google.com.
  10. ^ Heinz, Sven; Benner, Christopher; Spann, Nathanael; Bertolino, Eric; Lin, Yin C.; Laslo, Peter; Cheng, Jason X.; Murre, Cornelis; Singh, Harinder; Glass, Christopher K. (May 28, 2010). "Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities". Molecular Cell. 38 (4): 576–589. doi:10.1016/j.molcel.2010.05.004. PMC 2898526. PMID 20513432 – via PubMed.
  11. ^ a b c [2] Google Scholar Author profile, accessed March 30, 2021
  12. ^ Ricote, M.; Li, A. C.; Willson, T. M.; Kelly, C. J.; Glass, C. K. (January 1, 1998). "The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation". Nature. 391 (6662): 79–82. Bibcode:1998Natur.391...79R. doi:10.1038/34178. PMID 9422508. S2CID 4421986 – via PubMed.
  13. ^ Glass, C. K.; Witztum, J. L. (February 23, 2001). "Atherosclerosis. the road ahead". Cell. 104 (4): 503–516. doi:10.1016/s0092-8674(01)00238-0. PMID 11239408. S2CID 18061361 – via PubMed.

Glass Laboratory webpage