Bing Xia

Bing Xia is a scientist and professor at the Rutgers Cancer Research Institute New Jersey.^[1]. He is known for his discovery of PALB2 tumor suppressor gene.^[2]^[3]^[4]

Background

Xia was born and raised in China, in migrated to United States to pursue his graduate education at the University of Medicine and Dentistry New Jersey in 1996.^[1]^[5]

Work

Xia is a researcher focused on elucidating the the molecular mechanisms and path for PALB2/BRCA associated cancers with the goal of enhancing cancer treatment or prevention.^[1]^[6]^[7]

References

^ ^a ^b ^c "Bing Xia, PhD | Rutgers Cancer Institute of New Jersey". www.cinj.org. Retrieved 2021-09-15.
^ Ma, Jianglin; Cai, Hong; Wu, Tongde; Sobhian, Bijan; Huo, Yanying; Alcivar, Allen; Mehta, Monal; Cheung, Ka Lung; Ganesan, Shridar; Kong, Ah-Ng Tony; Zhang, Donna D. (April 2012). "PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function". Molecular and Cellular Biology. 32 (8): 1506–1517. doi:10.1128/MCB.06271-11. ISSN 1098-5549. PMC 3318596. PMID 22331464.
^ Xia, Bing; Sheng, Qing; Nakanishi, Koji; Ohashi, Akihiro; Wu, Jianmin; Christ, Nicole; Liu, Xinggang; Jasin, Maria; Couch, Fergus J.; Livingston, David M. (2006-06-23). "Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2". Molecular Cell. 22 (6): 719–729. doi:10.1016/j.molcel.2006.05.022. ISSN 1097-2765. PMID 16793542.
^ Xia, Bing; Dorsman, Josephine C.; Ameziane, Najim; de Vries, Yne; Rooimans, Martin A.; Sheng, Qing; Pals, Gerard; Errami, Abdellatif; Gluckman, Eliane; Llera, Julian; Wang, Weidong (February 2007). "Fanconi anemia is associated with a defect in the BRCA2 partner PALB2". Nature Genetics. 39 (2): 159–161. doi:10.1038/ng1942. ISSN 1061-4036. PMID 17200672.
^ Xia, Bing; Ke, Haiping; Shinde, Ujwal; Inouye, Masayori (2003-09-19). "The role of RbfA in 16S rRNA processing and cell growth at low temperature in Escherichia coli". Journal of Molecular Biology. 332 (3): 575–584. doi:10.1016/s0022-2836(03)00953-7. ISSN 0022-2836. PMID 12963368.
^ Foo, T K; Tischkowitz, M; Simhadri, S; Boshari, T; Zayed, N; Burke, K A; Berman, S H; Blecua, P; Riaz, N; Huo, Y; Ding, Y C (2017-03-20). "Compromised BRCA1–PALB2 interaction is associated with breast cancer risk". Oncogene. 36 (29): 4161–4170. doi:10.1038/onc.2017.46. ISSN 0950-9232.
^ Simhadri, Srilatha; Vincelli, Gabriele; Huo, Yanying; Misenko, Sarah; Foo, Tzeh Keong; Ahlskog, Johanna; Sørensen, Claus S.; Oakley, Gregory G.; Ganesan, Shridar; Bunting, Samuel F.; Xia, Bing (March 2019). "PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response". Oncogene. 38 (10): 1585–1596. doi:10.1038/s41388-018-0535-2. ISSN 1476-5594. PMC 6408219. PMID 30337689.

Bing Xia Article

[:0-1] "Bing Xia, PhD | Rutgers Cancer Institute of New Jersey". www.cinj.org. Retrieved 2021-09-15.

[2] Ma, Jianglin; Cai, Hong; Wu, Tongde; Sobhian, Bijan; Huo, Yanying; Alcivar, Allen; Mehta, Monal; Cheung, Ka Lung; Ganesan, Shridar; Kong, Ah-Ng Tony; Zhang, Donna D. (April 2012). "PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function". Molecular and Cellular Biology. 32 (8): 1506–1517. doi:10.1128/MCB.06271-11. ISSN 1098-5549. PMC 3318596. PMID 22331464.

[3] Xia, Bing; Sheng, Qing; Nakanishi, Koji; Ohashi, Akihiro; Wu, Jianmin; Christ, Nicole; Liu, Xinggang; Jasin, Maria; Couch, Fergus J.; Livingston, David M. (2006-06-23). "Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2". Molecular Cell. 22 (6): 719–729. doi:10.1016/j.molcel.2006.05.022. ISSN 1097-2765. PMID 16793542.

[4] Xia, Bing; Dorsman, Josephine C.; Ameziane, Najim; de Vries, Yne; Rooimans, Martin A.; Sheng, Qing; Pals, Gerard; Errami, Abdellatif; Gluckman, Eliane; Llera, Julian; Wang, Weidong (February 2007). "Fanconi anemia is associated with a defect in the BRCA2 partner PALB2". Nature Genetics. 39 (2): 159–161. doi:10.1038/ng1942. ISSN 1061-4036. PMID 17200672.

[5] Xia, Bing; Ke, Haiping; Shinde, Ujwal; Inouye, Masayori (2003-09-19). "The role of RbfA in 16S rRNA processing and cell growth at low temperature in Escherichia coli". Journal of Molecular Biology. 332 (3): 575–584. doi:10.1016/s0022-2836(03)00953-7. ISSN 0022-2836. PMID 12963368.

[6] Foo, T K; Tischkowitz, M; Simhadri, S; Boshari, T; Zayed, N; Burke, K A; Berman, S H; Blecua, P; Riaz, N; Huo, Y; Ding, Y C (2017-03-20). "Compromised BRCA1–PALB2 interaction is associated with breast cancer risk". Oncogene. 36 (29): 4161–4170. doi:10.1038/onc.2017.46. ISSN 0950-9232.

[7] Simhadri, Srilatha; Vincelli, Gabriele; Huo, Yanying; Misenko, Sarah; Foo, Tzeh Keong; Ahlskog, Johanna; Sørensen, Claus S.; Oakley, Gregory G.; Ganesan, Shridar; Bunting, Samuel F.; Xia, Bing (March 2019). "PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response". Oncogene. 38 (10): 1585–1596. doi:10.1038/s41388-018-0535-2. ISSN 1476-5594. PMC 6408219. PMID 30337689.

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