TRIM22

TRIM22
Identifiers
Aliases	TRIM22, GPSTAF50, RNF94, STAF50, tripartite motif containing 22
External IDs	OMIM: 606559; HomoloGene: 48399; GeneCards: TRIM22; OMA:TRIM22 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 5,689,697 bp End 5,737,089 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte spleen lymph node Achilles tendon granulocyte gallbladder palpebral conjunctiva appendix right uterine tube blood n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-macromolecule adaptor activity transcription corepressor activity DNA-binding transcription factor activity zinc ion binding metal ion binding protein binding protein kinase binding transferase activity Cellular component cytoplasm cytosol Cajal body nuclear speck intracellular anatomical structure nucleoplasm nucleus nuclear body Golgi apparatus Biological process regulation of transcription, DNA-templated positive regulation of autophagy interferon-gamma-mediated signaling pathway protein trimerization response to virus positive regulation of DNA-binding transcription factor activity transcription, DNA-templated regulation of protein localization positive regulation of NF-kappaB transcription factor activity defense response to virus protein ubiquitination immune response positive regulation of I-kappaB kinase/NF-kappaB signaling viral process negative regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10346 n/a Ensembl ENSG00000132274 n/a UniProt Q8IYM9 n/a RefSeq (mRNA) NM_006074 NM_001199573 n/a RefSeq (protein) NP_001186502 NP_006065 n/a Location (UCSC) Chr 11: 5.69 – 5.74 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Tripartite motif-containing 22, also known as TRIM22, is a human gene.

According to researcher Stephen Barr, a molecular virologist in the Department of Medical Microbiology and Immunology, gene TRIM22 prevents the assembly of the HIV virus.