SENP3
Appearance
Template:PBB SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a human gene that, together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regulation of ribosome biogenesis. SENP3 may be regulated by Arf-Mdm2-p53 pathway.[1]
References
Further reading
- Haindl M, Harasim T, Eick D; et al. (2008). "The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing
". EMBO reports. 9 (3): 273–279. PMID PMC2267381. {{cite journal}}
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- Kuo ML, den Besten W, Thomas MC; et al. (2008). "Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3". Cell Cycle. 7 (21): 3378–87. PMID 18948745.
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