Talk:Ketoacidosis

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Ketosis -> Ketoacidosis -> Undernutrion/Starvation

The entry discusses the link between diabetes or alcohol and Ketoacidosis, but only softly refers to starvation. Is it possible or probable to experience Ketoacidosis where insulin function is normal, but glucose or carbohydrate ingestion is extremely low? If not, why not? How does the manifestation of extreme Ketosis differ from Ketoacidosis if this circumstance doesn't lead to Ketoacidosis?

The real problem is that this article fails to address the role of ketoacidosis in the fasted state. Ketoacidosis occurs in a variety of situations that have nothing to do with diabetes or alcohol.

Is it extreme Ketosis or Ketoacidosis that sometimes occurs in children (especially females) and usually resolves by puberty? The already benign attributation to Ketosis with Ketoacidosis may further confuse, when this article is seperated from diabetic Ketoacidosis.

I don't think they should be merged into one article because the etiologies of diabeteic and other ketoacidoses are vastly different.--dp 17:54, 12 June 2007 (UTC)[reply]

Who maintains this page? Is this the same ketoacidosis as patients with Hyperemesis Gravidarum suffer? If so, a cyberlink would be logical.

Pathophysiology

I think the Pathophysiology section is misleading and needs a rewrite. For one it is exceedingly terse. But more significantly the disease process is really a combination of hyperglycemia with high levels of ketones. If the glucose levels are normal then there is no ketoacidosis. I believe this needs to be explained explicitly (i.e. this is what differentiates it from ketosis).

Comments?

--Mcorazao (talk) 04:26, 2 August 2008 (UTC)[reply]

I must say I agree it doesn't read very well, and appears to make at least one odd claim - that hyperglycaemia itself results in acidosis, as though glucose acted as an acid at blood pH. My understanding is that ketoacidosis is just what it says in the name: acidosis due to high level of ketones; DKA is ketoacidosis + hyperglycaemia, a medical emergency, and should probably have its own article. non-diabetic ketoacidosis means no relevant hyperglycaemia: the example given in the article would probably present with hypoglycaemia, as glucose generation is impaired.

So, I think you've got it wrong: hyperglycaemia distinguishes diabetic ketoacidosis from non-diabetic ketoacidosis. High ketone levels in the absence of acidosis would usually occur as a side effect of starvation or specifically Atkins-style "low carb" diets.

RandomP (talk) 12:30, 6 March 2009 (UTC)[reply]

Ketone breath

The article implies that the ketone breath odor occurs only in ketoacidosis, not ketosis. Is this true? If it is false, then the article contributes to confusion between ketoacidosis and ketosis. --Una Smith (talk) 22:47, 5 August 2008 (UTC)[reply]