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Tuberomammillary nucleus

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Tuberomammillary nucleus
Details
Identifiers
LatinNucleus tuberomamillaris
NeuroNames427
NeuroLex IDbirnlex_1271
TA98A14.1.08.932
TA25734
FMA62335
Anatomical terms of neuroanatomy

The tuberomammillary nucleus is a subnucleus of the posterior third of the hypothalamus. It consists of, largely, histaminergic neurons (i.e., neurones releasing histamine) and is involved with the control of arousal, sleep and circadian rhythm.

Axons of the tuberomammillary nucleus project primarily to the cerebral cortex, thalamus, basal ganglia, basal forebrain, and hypothalamus. The projections to the cerebral cortex directly increase cortical activation and arousal, and projections to acetylcholinergic neurons of the basal forebrain and dorsal pons do so indirectly, by increasing the release of acetylcholine in the cerebral cortex.

References

see, for example Kandel, Schwartz & Jessel, Principles of Neural Science, 4th Ed., p977.