Talk:Argyria

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Some of the text in this article was originally copied from http://www.atsdr.cdc.gov/toxprofiles/phs146.html which as a work of a U.S. Federal Government agaency without any other copyright notice should be in the public domain.

Blue Krishna

Lord Krishna, the blue-skinned Deity in Hindu mythology is described as having turned blue after consuming a quantity of poisoned river water in order to save humanity. Seeing as most myths have some grounding in real-life individuals, maybe Krishna could be mentioned as a possible high-profile argyria candidate? Throquzum (talk) 21:33, 19 April 2009 (UTC)[reply]

some references

Concerning the minimal amount of silver (to ingest) for becoming argyric:

Scientific refenrences:

argyria may occur after ingestion of 1.4 gr of silver over several month (silver nitrate in one particular case), 1.5 gr of silver within 14 days, up to 124 gr after 9 years and 200 gr after 10 month. (see Hill 1939, Wadhera 2005). Some scientist believes that argyria may come up after ingestion of only 1 gr silver (national health administration of Canada). Research on 70 cases of argyria by Gaud und Staud (1935) showed that the minimal amount of silver that induced argyria was 1.8 grams. Hill und Pillsbury think in 1939 that a total dose of 1 - 8 gr of inhaled silver dust may induce argyria and they say: ..The minimum amount of silver known to cause argyria in adults, from the use of any silver compound (including salts) is 900 mg of silver taken orally in one year". US-EPA writes: argyria is believed to occur at a total body burden of approximately 1 g Ag and above (EPA-440/4-81-017 (1981) 160 p).

People eating a huge number of Jintan Silver Pills breath freshener, a herbal product with silver coat 0,1 mg Ag / pill (at least 10 cases known and published in scientific journals) got argyria.

Local argyrosis cccured after: long time use of acupuncture-needles (Tanita 1985, Suzuki 1993, Takeishi 2002, Yamashita 2001) silvercontaining suture material silver earrings (van den Nieuwenhuijsen IJ 1988, Hendricks 1991, Sugden 2001) [4] silver "tattoo" around teeth, (seldom) after drilling work on silver amalgam fillings eye-argyrosis occured secondary to occupational silver soldering Redecke 00:39, 5 November 2005 (UTC)[reply]

The anonymous editor (you?) to this sentence, just striking what's overstricken here, made no sense:

" Studies in rats show that drinking water containing very large amounts of silver (~~9.8~~ grams of silver per U.S. gallon water or ~~2.6 grams~~ per liter) is likely to be life-threatening."

Of course, the sentence before then made no sense either. It would need not only the concentration of that solution, but how much of the solution at that concentration was ingested, to make any sense.

I have no problem if you take the whole thing out, pending provision of a source for the information, and the relevance of threatening the life of rats to the discussion at hand. Gene Nygaard 01:00, 5 November 2005 (UTC)[reply]

what i want to say is: we are not rats. and indeed: a concentration makes no sense of course. i do not know who wrote sentence that first... argyria is not life-threatening. we should talk about toxicology of silver on silver and not here. michael Redecke 02:15, 5 November 2005 (UTC)[reply]

argyria reversal

Source #1, the link about argyria reversal, is a dead link. Someone should fix this. Gary (talk) 02:19, 20 December 2007 (UTC)[reply]

It can't be permanent can it? —Preceding unsigned comment added by 75.72.21.221 (talk) 03:07, 10 January 2008 (UTC)[reply]

Silver Toxicity

Silver intoxication - Argyria - http://coseinteressanti.altervista.org/gold_silver.pdf

References in History Section

There seems to be a couple of paragraphs full of stated facts in the History section without a single reference. It would be nice to see some of these statements backed up with some evidence of their factuality.

What the machnism of turning blue

You didnt contain the most important information what is: why exactly skin turns blue, what is the biological mechanism of that? I'm not medicine doc so I dont know wheter the mechanism is known. But I would be really curiouse what are the hypothesis —Preceding unsigned comment added by 193.151.115.9 (talk) 09:53, 22 June 2009 (UTC)[reply]

Silver is deposited under the skin as nanoparticles, which are as a rule much darker in color than bulk silver (and often bluish, as well). Stonemason89 (talk) 17:57, 8 June 2010 (UTC)[reply]

My understanding is that the silver particles tarnish eventually, exactly like silver trophies etc will tarnish, and this results in the grey colour. If you have enough partcles concentrated in a particular patch of skin, the dark colour becomes visible from the outside. Wdford (talk) 07:25, 9 June 2010 (UTC)[reply]

Both may be true; the article on silver nanoparticles states: While frequently described as being 'silver' some are composed of a large percentage of silver oxide due to their large ratio of surface to bulk silver atoms. So you're probably right. Stonemason89 (talk) 01:52, 10 June 2010 (UTC)[reply]

Does this protect against sunburns?

Could silver work as a replacement for melanin, perhaps in people with albinism (or simply people who have the misfortune of being fair-skinned and thus more prone to sunburns and skin cancer)? I know it looks "weird" (grey, or blue-grey, instead of brown). But if the only other option is to risk getting (potentially deadly) melanoma, then maybe it wouldn't be so bad? Not that I would consider taking it myself, mind. Stonemason89 (talk) 19:53, 17 December 2009 (UTC)[reply]

Pictures, eyes

WTH? If this is to protect their identity, there are other ways. They look like right out of a zombie movie. At least explain that in the labels...--Cyberman TM (talk) 18:53, 22 July 2010 (UTC)[reply]

Agreed, it's terrifying. 38.105.101.2 (talk) 19:07, 11 August 2010 (UTC)[reply]

I must also agree - the black circles are explained in the captions now, but the images themselves are still unnerving - I'd say horrifying, personally, don't ask me why. Can this be changed to a black box spanning both eyes instead? A black rectangle seems to be reasonably standard for identity protection in other articles... and it won't be as freaky. (Note: I did consider that the circles were intentional, to show more of the face, but I don't see any noticeably worse discoloration in the areas that would be covered by a box, so hopefully it doesn't make a difference to the illustration. 76.177.42.68 (talk) 06:13, 8 January 2011 (UTC)[reply]

I agreed with the "sheesh, that's scary" sentiment and took about twenty seconds to add the bars the last guy was talking about. I have no idea how to add images to Wikipedia and I don't care enough to find out, so have fun with this http://img851.imageshack.us/img851/4711/argyria2.jpg 71.77.16.233 (talk) 03:15, 25 March 2011 (UTC)[reply]

Intentionally causing Argyria

I believe this article needs more information on the exact amounts needed to ingest daily to successfully cause argyria without poisoning oneself too much. Some of us actually want this and the lack of information on this subject is disappointing... 72.133.52.39 (talk)

Vandalism (made up myth)

I removed the following paragraph

http://en.wikipedia.org/w/index.php?title=Argyria&action=historysubmit&diff=474599148&oldid=467650172

because (for multiple reasons), this "myth" is almost certainly vandalism. (For example, Athena was a virgin.) If not, some reference of that myth in the corpus of greek mythology could have been found.

The paragraph in question had been introduced via the following edit:

http://en.wikipedia.org/w/index.php?title=Argyria&diff=prev&oldid=444105158

That user's only contributions were three edits to this article. — Preceding unsigned comment added by 193.136.60.53 (talk) 16:29, 2 February 2012 (UTC)[reply]

csfacts website

The website http://www.csfacts.com/pages/jones.html is used four times in the bit about Stan Jones. Is there any evidence that this is a reliable source for anything? It seems to be just a collection of largely pro-silver ingestion commentary and advertisements for cs products. If nobody objects I will remove it as a source and replace what I can from the abc and telegraph stories which are reliable.Desoto10 (talk) 03:20, 18 January 2013 (UTC)[reply]

Picture

The picture being used here is extremely misleading if it is indeed true that Argyria causes no peripheral symptoms. At the very least, someone needs to explain why the man in the picture is severely malnourished if not for the Argyria. Otherwise, let's find a depiction of a different person suffering from the disease. — Preceding unsigned comment added by 216.40.69.215 (talk) 20:04, 25 February 2013 (UTC)[reply]